Evidence map›Paper›PMID 23864543›Full record

ArticleEuropean child & adolescent psychiatry2014

Subthreshold traits of the broad autistic spectrum are distributed across different subgroups in parents, but not siblings, of probands with autism.

Laurence Robel, B Rousselot-Pailley, C Fortin, M Levy-Rueff, B Golse, B Falissard

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Article in European child & adolescent psychiatry, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Article
  6. Broader Autism Phenotype in Siblings of Children with ASD--A Review.International journal of molecular sciences · 2015
    Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Laurence RobelAPHP, Department of Child and Adolescent Psychiatry, Necker Enfant Malades Hospital, 149-162 rue de Sèvres, 75015, Paris, France. laurence.robel@free.fr.
B Rousselot-PailleyAPHP, Department of Child and Adolescent Psychiatry, Necker Enfant Malades Hospital, 149-162 rue de Sèvres, 75015, Paris, France.
C FortinAPHP, Department of Child and Adolescent Psychiatry, Necker Enfant Malades Hospital, 149-162 rue de Sèvres, 75015, Paris, France.
M Levy-RueffAPHP, Department of Child and Adolescent Psychiatry, Necker Enfant Malades Hospital, 149-162 rue de Sèvres, 75015, Paris, France.
B GolseAPHP, Department of Child and Adolescent Psychiatry, Necker Enfant Malades Hospital, 149-162 rue de Sèvres, 75015, Paris, France.
B FalissardINSERM 669 PSIGIAMP, 75013, Paris, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Autism is a categorical developmental disorder characterized by impairment in socialization, communication, and by restricted and circumscribed interests. Several authors have described the presence of subthreshold autistic traits in the general population, pervasive developmental disorders representing the extreme end of their distribution. In this study, we explored the presence of autistic traits in siblings and parents of a proband with autism, and in siblings and parents of a normally developing child, using the previously validated self-report French Autism Quotient, an adaptation of the AQ developed by S. Baron-Cohen. Scores were distributed between two main factors, F1 corresponding to socialization and communication, F2 to imagination and rigidity. Here, we show that both parents and siblings of a child with autism have more symptomatic scores in the domains of communication and socialization. In addition, we show that in these families the parents, but not the siblings, are distributed across different subcategories, according to their scores for the F1 and F2 domains. We hypothesize that these different subgroups may correspond to different underlying genetic mechanisms.

Indexed as

CommunicationGenetic Predisposition to DiseaseParentsSiblingsSocial BehaviorAutism Spectrum DisorderChildChild Development Disorders, PervasiveChild, PreschoolFamilyHumansInterpersonal RelationsLanguageMalePhenotypeSocializationAutism spectrum disordersBroader autism phenotypeParents and siblings

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.