Efficacy and safety of strontium ranelate in the treatment of knee osteoarthritis: results of a double-blind randomised, placebo-controlled trial.

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

Who cites it

12 citing papers in PubMed.

1. Nonclinical and clinical pharmacological characterization of the potent and selective cathepsin K inhibitor MIV-711.Journal of translational medicine · 2018
   Trial
2. The effect of vitamin D supplementation on knee osteoarthritis, the VIDEO study: a randomised controlled trial.Osteoarthritis and cartilage · 2016
   Trial
3. The role of TNFRSF11B in development of osteoarthritic cartilage.Rheumatology (Oxford, England) · 2022
   Article
4. Trabecular bone texture analysis of conventional radiographs in the assessment of knee osteoarthritis: review and viewpoint.Arthritis research & therapy · 2021
   Review
5. Imaging and Biochemical Markers for Osteoarthritis.Diagnostics (Basel, Switzerland) · 2021
   Article
6. Strontium promotes osteogenic differentiation by activating autophagy via the the AMPK/mTOR signaling pathway in MC3T3‑E1 cells.International journal of molecular medicine · 2019
   Article
7. Senescent cells and osteoarthritis: a painful connection.The Journal of clinical investigation · 2018
   Review
8. The selective cathepsin K inhibitor MIV-711 attenuates joint pathology in experimental animal models of osteoarthritis.Journal of translational medicine · 2018
   Article
9. New Drug Treatments for Osteoarthritis: What is on the Horizon?European medical journal. Rheumatology · 2017
   Article
10. Orthopedic tissue regeneration: cells, scaffolds, and small molecules.Drug delivery and translational research · 2016
    Review
11. On the predictive utility of animal models of osteoarthritis.Arthritis research & therapy · 2015
    Review
12. OsteoRheumatology: a new discipline?RMD open · 2015
    Article

Corrections and comments

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  Efficacy and safety of strontium ranelate in the treatment of knee osteoarthritis: results of a double-blind, randomised placebo-controlled trial.2013

Authors and funding

1 author.

Funding

No grant is acknowledged in the PubMed record.

Abstract

PubMed holds no abstract for this paper.

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