ArticleCanadian journal of gastroenterology = Journal canadien de gastroenterologie2013
Detection of adult celiac disease with duodenal screening biopsies over a 30-year period.
Article in Canadian journal of gastroenterology = Journal canadien de gastroenterologie, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed, 24 citations in OpenAlex.
- Adherence to guidelines, pitfalls, and emerging technologies in endoscopic practice for celiac disease: a nationwide SIGENP survey.European journal of pediatrics · 2026Article
- What does not look like celiac disease and instead it is.Gastroenterology and hepatology from bed to bench · 2023Article
- Review
- Endocrinopathies in celiac disease: When the endocrinologist sees what is invisible to the gastroenterologist.Acta bio-medica : Atenei Parmensis · 2018Review
- Role of biopsy in diagnosis and treatment of adult celiac disease.Gastroenterology and hepatology from bed to bench · 2018Review
- The serological diagnosis of adult coeliac disease - a cautious step forward?Gastroenterology and hepatology from bed to bench · 2018Article
- Dietary compliance in celiac disease.World journal of gastroenterology · 2017Article
- Is duodenal biopsy appropriate in areas endemic forNorthern clinics of Istanbul · 2017Article
- Endocrine manifestations in celiac disease.World journal of gastroenterology · 2016Review
- Iron deficiency anemia in celiac disease.World journal of gastroenterology · 2015Review
- Celiac disease: a disorder emerging from antiquity, its evolving classification and risk, and potential new treatment paradigms.Gut and liver · 2015Review
- Non-dietary forms of treatment for adult celiac disease.World journal of gastrointestinal pharmacology and therapeutics · 2013Review
- Routine duodenal biopsies to diagnose celiac disease.Canadian journal of gastroenterology = Journal canadien de gastroenterologie · 2013Article
Corrections and comments
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Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundSerological studies suggest that celiac disease may be present in approximately 0.5% to 1% of the North American population. Screening data based on small intestinal biopsy performed during routine endoscopic evaluations are not available.
methodsPatients referred between January 1982 and December 2011 for evaluation of gastrointestinal symptoms and requiring elective investigative upper endoscopic evaluation underwent duodenal biopsies to determine whether changes of adult celiac disease were present.
resultsA total of 9665 patients, including 4008 (41.5%) males and 5657 (68.5%) females, underwent elective endoscopies and duodenal biopsies. Of these, 234 (2.4%) exhibited changes of celiac disease including 73 males (1.8%) and 161 females (2.8%). During the first 20 years, the number of biopsy-positive patients in five-year intervals progressively decreased and, subsequently, during the next 10 years, the number progressively increased.
conclusionsCeliac disease is far more common in specialist practice than has been suggested in the evaluation of healthy populations using serological screening studies. Endoscopic duodenal biopsy is an important method of identifying underlying celiac disease and should be routinely considered in all patients undergoing an elective endoscopic evaluation. Noninherited factors, possibly environmental, may play a role in the appearance of biopsy-defined celiac disease and alter detection over time.
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