ArticlePloS one2013
Seasonal and temporal variation in release of antibiotics in hospital wastewater: estimation using continuous and grab sampling.
Article in PloS one, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed.
- Thermal Shifts Dominate Single-Gene Responses to Transcription-Targeting Antibiotics.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Early detection of nosocomial pathogens in air and surfaces using an innovative genetic approach for surveillance in healthcare settings.Antimicrobial resistance and infection control · 2026Article
- Grow now, pay later: When should a bacterium go into debt?Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- Mapping the scarcity of data on antibiotics in natural and engineered water environments across India.Frontiers in antibiotics · 2024Review
- Identifying Environmental Impact Factors for Sustainable Healthcare: A Scoping Review.International journal of environmental research and public health · 2023Article
- Utility of constructed wetlands for treatment of hospital effluent and antibiotic resistant bacteria in resource limited settings: A case study in Ujjain, India.Water environment research : a research publication of the Water Environment Federation · 2022Article
- The occurrence of antimicrobial residues and antimicrobial resistance genes in urban drinking water and sewage in Southern Brazil.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2022Article
- Wastewater treatment plant operators report high capacity to support wastewater surveillance for COVID-19 across New York State, USA.The Science of the total environment · 2022Article
- The optimization of enzymatic oxidation of levofloxacin, a fluoroquinolone antibiotic for wastetwater treatment.Biodegradation · 2021Article
- Article
- Fate of Macrolide Antibiotics with Different Wastewater Treatment Technologies.Water, air, and soil pollution · 2021Article
- Electroporation as an Efficacy Potentiator for Antibiotics With Different Target Sites.Frontiers in microbiology · 2021Article
- Monitoring of Water Quality, Antibiotic Residues, and Antibiotic-ResistantInternational journal of environmental research and public health · 2020Article
- Antimicrobials and Antimicrobial Resistance in the Environment and Its Remediation: A Global One Health Perspective.International journal of environmental research and public health · 2019Article
- Repeated Isolation of Extended-Spectrum-β-Lactamase-PositiveAntimicrobial agents and chemotherapy · 2019Article
- Sewage effluent from an Indian hospital harbors novel carbapenemases and integron-borne antibiotic resistance genes.Microbiome · 2019Article
- Seasonal Variations in Water-Quality, Antibiotic Residues, Resistant Bacteria and Antibiotic Resistance Genes ofInternational journal of environmental research and public health · 2018Article
- Electrochemical treatment of penicillin, cephalosporin, and fluoroquinolone antibiotics via active chlorine: evaluation of antimicrobial activity, toxicity, matrix, and their correlation with the degradation pathways.Environmental science and pollution research international · 2017Article
- Ecotoxicological risk assessment and seasonal variation of some pharmaceuticals and personal care products in the sewage treatment plant and surface water bodies (lakes).Environmental monitoring and assessment · 2017Article
- A Three-Year Follow-Up Study of Antibiotic and Metal Residues, Antibiotic Resistance and Resistance Genes, Focusing on Kshipra-A River Associated with Holy Religious Mass-Bathing in India: Protocol Paper.International journal of environmental research and public health · 2017Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The presence of antibiotics in the environment and their subsequent impact on resistance development has raised concerns globally. Hospitals are a major source of antibiotics released into the environment. To reduce these residues, research to improve knowledge of the dynamics of antibiotic release from hospitals is essential. Therefore, we undertook a study to estimate seasonal and temporal variation in antibiotic release from two hospitals in India over a period of two years. For this, 6 sampling sessions of 24 hours each were conducted in the three prominent seasons of India, at all wastewater outlets of the two hospitals, using continuous and grab sampling methods. An in-house wastewater sampler was designed for continuous sampling. Eight antibiotics from four major antibiotic groups were selected for the study. To understand the temporal pattern of antibiotic release, each of the 24-hour sessions were divided in three sub-sampling sessions of 8 hours each. Solid phase extraction followed by liquid chromatography/tandem mass spectrometry (LC-MS/MS) was used to determine the antibiotic residues. Six of the eight antibiotics studied were detected in the wastewater samples. Both continuous and grab sampling methods indicated that the highest quantities of fluoroquinolones were released in winter followed by the rainy season and the summer. No temporal pattern in antibiotic release was detected. In general, in a common timeframe, continuous sampling showed less concentration of antibiotics in wastewater as compared to grab sampling. It is suggested that continuous sampling should be the method of choice as grab sampling gives erroneous results, it being indicative of the quantities of antibiotics present in wastewater only at the time of sampling. Based on our studies, calculations indicate that from hospitals in India, an estimated 89, 1 and 25 ng/L/day of fluroquinolones, metronidazole and sulfamethoxazole respectively, might be getting released into the environment per 100 hospital beds.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.