Evidence map›Paper›PMID 23861758›Full record

ArticlePloS one2013

3-dimensional diffusion tensor imaging (DTI) atlas of the rat brain.

Ashley Rumple, Matthew McMurray, Josephine Johns, Jean Lauder, Pooja Makam, Marlana Radcliffe, Ipek Oguz

Abstract read
In one paragraph

Article in PloS one, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Article
  4. The brainstem connectome database.Scientific data · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Ashley RumpleUNC Chapel Hill, Chapel Hill, North Carolina, USA. rumple@ad.unc.edu
Matthew McMurray
Josephine Johns
Jean Lauder
Pooja Makam
Marlana Radcliffe
Ipek Oguz

Funding

UNC MRDD Research CenterP30HD003110 · NICHD · UNIV OF NORTH CAROLINA CHAPEL HILL · PI BELGER, AYSENIL · 1985 to 2012
$28.7M
PRENATAL COCAINE AND NEUROBEHAVIORAL FACTORS UNDERLYING MOTHER-INFANT INTERACTIONP01DA022446 · NIDA · UNIV OF NORTH CAROLINA CHAPEL HILL · PI JOHNS, JOSEPHINE M. · 2008 to 2015
$10.2M
High Throughput web-base Image Analysis of Mouse Brain MR Imaging StudiesR41NS059095 · NINDS · KITWARE, INC. · PI STYNER, MARTIN ANDREAS · 2007 to 2008
$397k
Prenatal Cocaine Exposure: Neurological and Behavioral Effects in RatsF31DA026251 · NIDA · UNIV OF NORTH CAROLINA CHAPEL HILL · PI MCMURRAY, MATTHEW S. · 2009 to 2010
$56k
NICHD NIH HHS HD 03110NICHD NIH HHS P30 HD003110NIDA NIH HHS F31 DA026251NIDA NIH HHS F31DA026251NIDA NIH HHS P01 DA022446NINDS NIH HHS R41 NS059095
6 · The paper itself

Abstract

Anatomical atlases play an important role in the analysis of neuroimaging data in rodent neuroimaging studies. Having a high resolution, detailed atlas not only can expand understanding of rodent brain anatomy, but also enables automatic segmentation of new images, thus greatly increasing the efficiency of future analysis when applied to new data. These atlases can be used to analyze new scans of individual cases using a variety of automated segmentation methods. This project seeks to develop a set of detailed 3D anatomical atlases of the brain at postnatal day 5 (P5), 14 (P14), and adults (P72) in Sprague-Dawley rats. Our methods consisted of first creating a template image based on fixed scans of control rats, then manually segmenting various individual brain regions on the template. Using itk-SNAP software, subcortical and cortical regions, including both white matter and gray matter structures, were manually segmented in the axial, sagittal, and coronal planes. The P5, P14, and P72 atlases had 39, 45, and 29 regions segmented, respectively. These atlases have been made available to the broader research community.

Indexed as

Diffusion Tensor ImagingImaging, Three-DimensionalNeuroimagingAnimalsBrainFemaleImage Processing, Computer-AssistedMaleRats

Identifiers

PMID23861758
PMCPMC3702494

What OpenQuestion holds

Textmetadata
LicenceCC0
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.