ArticlePloS one2013
Transcriptional activation of c3 and hsp70 as part of the immune response of Acropora millepora to bacterial challenges.
Article in PloS one, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
18 citing papers in PubMed, 53 citations in OpenAlex.
- Heatwave-driven persistent microbes threaten the resilience of Mediterranean coral holobionts.Environmental microbiome · 2025Article
- Global warming-related response after bacterial challenge in Astroides calycularis, a Mediterranean thermophilic coral.Scientific reports · 2024Article
- Holobiont responses of mesophotic precious red coral Corallium rubrum to thermal anomalies.Environmental microbiome · 2023Article
- Does Predation Exacerbate the Risk of Endosymbiont Loss in Heat Stressed Hermatypic Corals? Molecular Cues Provide Insights Into Species-Specific Health Outcomes in a Multi-Stressor Ocean.Frontiers in physiology · 2022Article
- Thermal stress-induced oxidative damages in the liver and associated death in fish, Labeo rohita.Fish physiology and biochemistry · 2021Article
- Differential gene expression analysis of symbiotic and aposymbioticEcology and evolution · 2019Article
- Transcriptomic analysis reveals protein homeostasis breakdown in the coral Acropora millepora during hypo-saline stress.BMC genomics · 2019Article
- Altered Immune Landscape and Disrupted Coral-Frontiers in physiology · 2019Article
- Influence of Chemotaxis and Swimming Patterns on the Virulence of the Coral Pathogen Vibrio coralliilyticus.Journal of bacteriology · 2018Article
- Article
- The cellular stress response of the scleractinian coral Goniopora columna during the progression of the black band disease.Cell stress & chaperones · 2017Article
- Physiological plasticity related to zonation affects hsp70 expression in the reef-building coral Pocillopora verrucosa.PloS one · 2017Article
- The Role of Complement in Cnidarian-Dinoflagellate Symbiosis and Immune Challenge in the Sea Anemone Aiptasia pallida.Frontiers in microbiology · 2016Article
- Defending against pathogens - immunological priming and its molecular basis in a sea anemone, cnidarian.Scientific reports · 2015Article
- Gene expression associated with white syndromes in a reef building coral, Acropora hyacinthus.BMC genomics · 2015Article
- Comparative immune responses of corals to stressors associated with offshore reef-based tourist platforms.Conservation physiology · 2015Article
- Potential Response to Selection of HSP70 as a Component of Innate Immunity in the Abalone Haliotis rufescens.PloS one · 2015Article
- Vibrio coralliilyticus strain OCN008 is an etiological agent of acute Montipora white syndrome.Applied and environmental microbiology · 2014Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The impact of disease outbreaks on coral physiology represents an increasing concern for the fitness and resilience of reef ecosystems. Predicting the tolerance of corals to disease relies on an understanding of the coral immune response to pathogenic interactions. This study explored the transcriptional response of two putative immune genes (c3 and c-type lectin) and one stress response gene (hsp70) in the reef building coral, Acropora millepora challenged for 48 hours with bacterial strains, Vibrio coralliilyticus and Alteromonas sp. at concentrations of 10(6) cells ml(-1). Coral fragments challenged with V. coralliilyticus appeared healthy while fragments challenged with Alteromonas sp. showed signs of tissue lesions after 48 hr. Coral-associated bacterial community profiles assessed using denaturing gradient gel electrophoresis changed after challenge by both bacterial strains with the Alteromonas sp. treatment demonstrating the greatest community shift. Transcriptional profiles of c3 and hsp70 increased at 24 hours and correlated with disease signs in the Alteromonas sp. treatment. The expression of hsp70 also showed a significant increase in V. coralliilyticus inoculated corals at 24 h suggesting that even in the absence of disease signs, the microbial inoculum activated a stress response in the coral. C-type lectin did not show a response to any of the bacterial treatments. Increase in gene expression of c3 and hsp70 in corals showing signs of disease indicates their potential involvement in immune and stress response to microbial challenges.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.