Evidence map›Paper›PMID 23861689›Full record

ArticleInternational journal of pediatrics2013

Maternal BMI, IGF-I Levels, and Birth Weight in African American and White Infants.

Adriana C Vidal, Amy P Murtha, Susan K Murphy, Kimberly Fortner, Francine Overcash, Nikki Henry, Joellen M Schildkraut, Michele R Forman, Wendy Demark-Wahnefried, Joanne Kurtzberg and 2 more

Open access · goldAbstract read
In one paragraph

Article in International journal of pediatrics, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.5field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 6 institutions in 1 country.

Adriana C VidalDepartment of Obstetrics and Gynecology and Program of Cancer Detection, Prevention and Control, Duke University School of Medicine, Durham, NC 27710, USA.
Amy P Murtha
Susan K Murphy
Kimberly Fortner
Francine Overcash
Nikki Henry
Joellen M Schildkraut
Michele R Forman
Wendy Demark-Wahnefried
Joanne Kurtzberg
Randy Jirtle
Cathrine Hoyo
Duke University · USDuke Medical Center · USDuke University Hospital · USThe University of Texas at Austin · USUniversity of Alabama at Birmingham · USVanderbilt University · US

Funding

Nutrition, Deregulation of Imprinted GenesR01ES016772 · NIEHS · DUKE UNIVERSITY · PI HOYO, CATHRINE · 2009 to 2013
$3.1M
Disparities in cervical cancer precursors and deregulation of imprinted genesR01CA142983 · NCI · NORTH CAROLINA STATE UNIVERSITY RALEIGH · PI HOYO, CATHRINE, MURPHY, SUSAN KAY · 2010 to 2014
$3.0M
NCI NIH HHS R01 CA142983NIEHS NIH HHS R01 ES016772
6 · The paper itself

Abstract

At birth, elevated IGF-I levels have been linked to birth weight extremes; high birth weight and low birth weight are risk factors for adult-onset chronic diseases including obesity, cardiovascular disease, and type 2 diabetes. We examined associations between plasma IGF-I levels and birth weight among infants born to African American and White obese and nonobese women. Prepregnancy weight and height were assessed among 251 pregnant women and anthropometric measurements of full term infants (≥37 weeks of gestation) were taken at birth. Circulating IGF-I was measured by ELISA in umbilical cord blood plasma. Linear regression models were utilized to examine associations between birth weight and high IGF-I, using the bottom two tertiles as referents. Compared with infants with lower IGF-I levels (≤3rd tertile), those with higher IGF-I levels (>3rd tertile) were 130 g heavier at birth, (β-coefficient = 230, se = 58.0, P = 0.0001), after adjusting for gender, race/ethnicity, gestational age, delivery route, maternal BMI and smoking. Stratified analyses suggested that these associations are more pronounced in infants born to African American women and women with BMI ≥30 kg/m(2); the cross product term for IGF-I and maternal BMI was statistically significant (P ≤ 0.0004). Our findings suggest that the association between IGF-I levels and birth weight depends more on maternal obesity than African American race/ethnicity.

Identifiers

PMID23861689
PMCPMC3686113
OpenAlexW2102952721

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.