Evidence map›Paper›PMID 23861565›Full record

ArticleBioinformation2013

SVM based model generation for binding site prediction on helix turn helix motif type of transcription factors in eukaryotes.

Koel Mukherjee, Abhipriya, Ambarish Saran Vidyarthi, Dev Mani Pandey

Abstract read
In one paragraph

Article in Bioinformation, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Koel MukherjeeDepartment of Biotechnology, Birla Institute of Technology, Mesra, Ranchi-835 215, Jharkhand, India.
Abhipriya
Ambarish Saran Vidyarthi
Dev Mani Pandey

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Support vector machine is a class of machine learning algorithms which uses a set of related supervised learning methods for classification and regression. Nowadays this method is vividly applied to many detection problems related with secondary structure, tumor cell and binding residue prediction. In this work, support vector machines (SVMs) have been trained on 90 sequences of transcription factors with HTH motif. Four sequence features were used as attribute for the prediction of interaction site in HTH motif. A web page was also developed so that user can easily enter the protein sequence and receive the output as interaction site predicted or not predicted. The generated model shows a very high amount of accuracy, sensitivity and specificity which proves to be a good model for the selected case.

Indexed as

confusion matrixhelix turn helix motifmachine learning algorithmSupport vector machine

Identifiers

PMID23861565
PMCPMC3705624

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.