Evidence map›Paper›PMID 23861437›Full record

ReviewThe Journal of biological chemistry2013

The redox proteome.

Young-Mi Go, Dean P Jones

Open access · hybridAbstract readReview
In one paragraph

Review in The Journal of biological chemistry, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 144 papers.

0numbers the graph read from it
0cells of the map it votes in
144citing papers in PubMed
12.3field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

144 citing papers in PubMed, 254 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Article
  6. Proteoforms as the true units of physiological function.European journal of applied physiology · 2026
    Review
  7. Article
  8. Article
  9. Review
  10. Hydrogen sulfide/polysulfides signaling and neuronal diseases.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2025
    Review
  11. Electrochemistry as a Tool for Redox-Based Bio-Information Processing.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Article
  12. Article
  13. Article
  14. Article
  15. Review
  16. Review
  17. Redox Regulation of KAntioxidants & redox signaling · 2024
    Review
  18. Fundamentals of redox regulation in biology.Nature reviews. Molecular cell biology · 2024
    Review
  19. Redox organization of living systems.Free radical biology & medicine · 2024
    Review
  20. Article

84 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Young-Mi GoFrom the Division of Pulmonary, Allergy, and Critical Care Medicine, Department of Medicine, Emory University, Atlanta, Georgia 30322.
Dean P Jones
Emory University · US

Funding

Metabolomics of subclinical and clinical cardiovascular diseaseP20HL113451 · NHLBI · EMORY UNIVERSITY · PI JONES, DEAN PAUL · 2012 to 2016
$4.3M
Thioredoxin-2 protection against mitochondrial oxidative toxicityR01ES009047 · NIEHS · EMORY UNIVERSITY · PI JONES, DEAN PAUL · 1998 to 2013
$3.9M
A metabolomic model of aging in the common marmosetR01AG038746 · NIA · EMORY UNIVERSITY · PI JONES, DEAN PAUL, PROMISLOW, DANIEL EDWARD · 2010 to 2014
$2.5M
NHLBI NIH HHS HL113451NHLBI NIH HHS P20 HL113451NIA NIH HHS AG038746NIA NIH HHS R01 AG038746NIEHS NIH HHS ES009047NIEHS NIH HHS R01 ES009047
6 · The paper itself

Abstract

The redox proteome consists of reversible and irreversible covalent modifications that link redox metabolism to biologic structure and function. These modifications, especially of Cys, function at the molecular level in protein folding and maturation, catalytic activity, signaling, and macromolecular interactions and at the macroscopic level in control of secretion and cell shape. Interaction of the redox proteome with redox-active chemicals is central to macromolecular structure, regulation, and signaling during the life cycle and has a central role in the tolerance and adaptability to diet and environmental challenges.

Indexed as

Oxidation-ReductionProteomeActinsAnimalsCysteineGlutathioneHumansMacromolecular SubstancesMetabolomeProteomicsSignal TransductionSulfhydryl CompoundsThioredoxinsActinsCysteineGlutathioneMacromolecular SubstancesProteomeSulfhydryl CompoundsThioredoxinsGlutathioneRedox RegulationSystems BiologyThiolThioredoxin

Identifiers

PMID23861437
PMCPMC3772199
OpenAlexW2093592040

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.