Evidence map›Paper›PMID 23861293›Full record

Trial reportCancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology2013

No effect of exercise on urinary 6-sulfatoxymelatonin and catecholamines in young women participating in a 16-week randomized controlled trial.

Andrea Y Arikawa, William Thomas, Sanjay R Patel, Mindy S Kurzer

Open access · bronzeAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
0.6field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 10 citations in OpenAlex.

  1. Pooled it
  2. Effects of physical activity on melatonin levels in previously sedentary men and women.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2014
    Trial
  3. Linking Physical Activity to Breast Cancer via Sex Hormones, Part 1: The Effect of Physical Activity on Sex Steroid Hormones.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2022
    Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Andrea Y ArikawaDepartment of Food Science and Nutrition, University of Minnesota, Saint Paul, MN 55108, USA. aarikawa@umn.edu
William Thomas
Sanjay R Patel
Mindy S Kurzer
Brigham and Women's Hospital · USUniversity of Minnesota · US

Funding

YOUTH DRUG ABUSE, ADHD, AND RELATED DISRUPTIVE DISORDERSM01RR000400 · NCRR · UNIVERSITY OF MINNESOTA TWIN CITIES · PI BACHANOVA, VERONIKA S · 1985 to 2009
$33.7M
Exercise effects on melatonin and sleep in young womenR21CA137242 · NCI · UNIVERSITY OF MINNESOTA · PI ARIKAWA, ANDREA Y. · 2010 to 2011
$366k
NCI NIH HHS R21 CA137242NCRR NIH HHS M01 RR000400NCRR NIH HHS M01-RR00400
6 · The paper itself

Abstract

backgroundWomen with breast cancer have decreased levels of melatonin or its metabolite in plasma and/or urine.

methodsWe measured serum melatonin, urinary 6-sulfatoxymelatonin, catecholamines, and cortisol in 141 sedentary young female participants in a clinical trial comparing 150 min/wk aerobic exercise for 4 months to no-exercise controls. Demographics, health surveys, body composition, sleep quality, fitness levels, and blood and urine samples were obtained at baseline and 16 weeks.

resultsThere were no differences between groups at baseline in demographics, exercise, sleep habits, or study hormones. There were also no significant differences between groups in any of the hormones at 16 weeks.

conclusionSixteen weeks of exercise had minimal effects on melatonin secretion of young women. IMPACT: There is convincing evidence that exercise protects against breast cancer, but this does not appear to occur through changes in melatonin secretion.

Indexed as

AdolescentAdultBreast NeoplasmsCatecholaminesEnzyme-Linked Immunosorbent AssayExerciseFemaleHumansMelatoninYoung Adult6-sulfatoxymelatoninCatecholaminesMelatonin

Identifiers

PMID23861293
PMCPMC3769436
OpenAlexW2106538242

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.