ReviewCurrent HIV/AIDS reports2013
HIV and neurocognitive dysfunction.
Review in Current HIV/AIDS reports, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02663934 (Exercise Training to Improve Brain Health in Older HIV+ Individuals), which is not on this map. Cited by 43 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Exercise Training to Improve Brain Health in Older HIV+ Individuals
Who cites it
43 citing papers in PubMed.
- Limited correlation between systemic biomarkers and neurocognitive performance before and during HIV treatment.Journal of neurovirology · 2020Trial
- HIV, Inflammation, and Immunometabolism: A Model of the Inflammatory Theory of Disease.Viruses · 2025Review
- Article
- Neurocognitive Function Domains Are Not Affected in Active Professional Male Footballers, but Attention Deficits and Impairments Are Associated with Concussion.Sports (Basel, Switzerland) · 2024Article
- Machine learning for predicting cognitive deficits using auditory and demographic factors.PloS one · 2024Article
- Risk of Falls in HIV-Infected Patients on Antiretroviral Therapy and Its Associated Factors.HIV/AIDS (Auckland, N.Z.) · 2022Article
- Increased IL-6 expression precedes reliable viral detection in the rhesus macaque brain during acute SIV infection.JCI insight · 2021Article
- Effects of integrase inhibitor-based antiretroviral therapy on brain outcomes according to time since acquisition of HIV-1 infection.Scientific reports · 2021Observational
- Treating viruses in the brain: Perspectives from NeuroAIDS.Neuroscience letters · 2021Review
- The Block-and-Lock Strategy for Human Immunodeficiency Virus Cure: Lessons Learned from Didehydro-Cortistatin A.The Journal of infectious diseases · 2021Review
- Dopamine Levels Induced by Substance Abuse Alter Efficacy of Maraviroc and Expression of CCR5 Conformations on Myeloid Cells: Implications for NeuroHIV.Frontiers in immunology · 2021Article
- Family Contextual Factors are Differentially Associated with Depressive Symptoms among Boys and Girls with Perinatally Acquired HIV.AIDS and behavior · 2021Article
- Efficacy, pharmacokinetics and neurocognitive performance of dual, NRTI-sparing antiretroviral therapy in acute HIV-infection.AIDS (London, England) · 2020Article
- Diffusion tensor magnetic resonance imaging of white matter integrity in patients with HIV-associated neurocognitive disorders.Annals of translational medicine · 2020Article
- Article
- Role of T Lymphocytes in HIV Neuropathogenesis.Current HIV/AIDS reports · 2019Review
- HIV-1 Tat enhances purinergic P2Y4 receptor signaling to mediate inflammatory cytokine production and neuronal damage via PI3K/Akt and ERK MAPK pathways.Journal of neuroinflammation · 2019Article
- Plasma HIV RNA level is associated with neurocognitive function among HIV-1-infected patients in Nigeria.Journal of neurovirology · 2018Article
- Large-Scale Validation of Hypothesis Generation Systems via Candidate Ranking.Proceedings : ... IEEE International Conference on Big Data. IEEE International Conference on Big Data · 2018Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The spectrum of HIV-associated neurocognitive disorder (HAND) has been dramatically altered in the setting of widely available effective antiretroviral therapy (ART). Once culminating in dementia in many individuals infected with HIV, HAND now typically manifests as more subtle, though still morbid, forms of cognitive impairment in persons surviving long-term with treated HIV infection. Despite the substantial improvement in severity of this disorder, the fact that neurologic injury persists despite ART remains a challenge to the community of patients, providers and investigators aiming to optimize quality of life for those living with HIV. Cognitive dysfunction in treated HIV may reflect early irreversible CNS injury accrued before ART is typically initiated, ongoing low-level CNS infection and progressive injury in the setting of ART, or comborbidities including effects of treatment which may confound the beneficial reduction in viral replication and immune activation effected by ART.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.