Evidence map›Paper›PMID 23860766›Full record

ArticlemBio2013

Influenza viruses: breaking all the rules.

Jeffery K Taubenberger, David M Morens

Abstract read
In one paragraph

Article in mBio, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Review
  5. The 1918 Influenza Pandemic and Its Legacy.Cold Spring Harbor perspectives in medicine · 2020
    Review
  6. Review
  7. Article
  8. Article
  9. Article
  10. Mathematical Analysis of Influenza A Dynamics in the Emergence of Drug Resistance.Computational and mathematical methods in medicine · 2018
    Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. State of the Globe: The H1N1 Threat Continues to Loom the Planet.Journal of global infectious diseases · 2013
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Jeffery K TaubenbergerViral Pathogenesis and Evolution Section, Laboratory of Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, USA. taubenbergerj@niaid.nih.gov
David M Morens

Funding

Influenza Viral PathogenesisZIAAI000986 · NIAID · NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES · PI TAUBENBERGER, JEFFERY · 2009 to 2025
$30.0M
Intramural NIH HHS
6 · The paper itself

Abstract

Influenza A viruses (IAV) are significant pathogens able to repeatedly switch hosts to infect multiple avian and mammalian species, including humans. The unpredictability of IAV evolution and interspecies movement creates continual public health challenges, such as the emergence of the 2009 pandemic H1N1 virus from swine, as well as pandemic threats from the ongoing H5N1 and the recent H7N9 epizootics. In the last decade there has been increased concern about the "dual use" nature of microbiology, and a set of guidelines covering "dual use research of concern" includes seven categories of potentially problematic scientific experiments. In this Perspective, we consider how in nature IAV continually undergo "dual use experiments" as a matter of evolution and selection, and we conclude that studying these properties of IAV is critical for mitigating and preventing future epidemics and pandemics.

Indexed as

Evolution, MolecularHost SpecificityMutationAnimalsHumansInfluenza A virusInfluenza, HumanOrthomyxoviridae InfectionsViral Tropism

Identifiers

PMID23860766
PMCPMC3735197

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.