ArticleThe Pediatric infectious disease journal2013
Undervaccination of perinatally HIV-infected and HIV-exposed uninfected children in Latin America and the Caribbean.
Article in The Pediatric infectious disease journal, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed.
- Immunogenicity and safety of a hexavalent pediatric vaccine in HIV-exposed infected and uninfected infants in Republic of South Africa.Human vaccines & immunotherapeutics · 2021Trial
- Gaps in knowledge about the vaccine coverage of immunocompromised children: a scoping review.Human vaccines & immunotherapeutics · 2022Article
- Determinants of vaccine uptake in HIV-affected families from West Bengal.Human vaccines & immunotherapeutics · 2021Article
- Levels of vaccination coverage among HIV-exposed children in China: a retrospective study.Infectious diseases of poverty · 2021Article
- Immunity After Childhood Vaccinations in Perinatally HIV-exposed Children With and Without HIV Infection in Latin America.The Pediatric infectious disease journal · 2018Article
- Article
- Low vaccine coverage among children born to HIV infected women in Niamey, Niger.Human vaccines & immunotherapeutics · 2016Article
- Immunity to Measles, Mumps, and Rubella in US Children With Perinatal HIV Infection or Perinatal HIV Exposure Without Infection.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2015Article
- Temporal trends in mortality and loss to follow-up among children enrolled in Côte d'Ivoire's national antiretroviral therapy program.The Pediatric infectious disease journal · 2014Article
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Authors and funding
14 authors.
Funding
Abstract
backgroundPerinatally HIV-infected (PHIV) children may be at risk of undervaccination. Vaccination coverage rates among PHIV and HIV-exposed uninfected (HEU) children in Latin America and the Caribbean were compared.
methodsAll PHIV and HEU children born from 2002 to 2007 who were enrolled in a multisite observational study conducted in Latin America and the Caribbean were included in this analysis. Children were classified as up to date if they had received the recommended number of doses of each vaccine at the appropriate intervals by 12 and 24 months of age. Fisher's exact test was used to analyze the data. Covariates potentially associated with a child's HIV status were considered in multivariable logistic regression modeling.
resultsOf 1156 eligible children, 768 (66.4%) were HEU and 388 (33.6%) were PHIV. HEU children were significantly (P < 0.01) more likely to be up to date by 12 and 24 months of age for all vaccines examined. Statistically significant differences persisted when the analyses were limited to children enrolled before 12 months of age. Controlling for birth weight, sex, primary caregiver education and any use of tobacco, alcohol or illegal drugs during pregnancy did not contribute significantly to the logistic regression models.
conclusionsPHIV children were significantly less likely than HEU children to be up to date for their childhood vaccinations at 12 and 24 months of age, even when limited to children enrolled before 12 months of age. Strategies to increase vaccination rates in PHIV are needed.
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