Evidence map›Paper›PMID 23860031›Full record

ReviewJournal of neuropathology and experimental neurology2013

MicroRNAs in cerebral ischemia-induced neurogenesis.

Xian Shuang Liu, Michael Chopp, Rui Lan Zhang, Zheng Gang Zhang

Open access · bronzeAbstract readReview
In one paragraph

Review in Journal of neuropathology and experimental neurology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers.

0numbers the graph read from it
0cells of the map it votes in
46citing papers in PubMed
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

46 citing papers in PubMed, 70 citations in OpenAlex.

  1. Article
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  15. Exosome-mediated miRNA delivery promotes liver cancer EMT and metastasis.American journal of translational research · 2020
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Xian Shuang LiuDepartment of Neurology, Henry Ford Health System, Detroit, MI 48202, USA.
Michael Chopp
Rui Lan Zhang
Zheng Gang Zhang
Henry Ford Health System · USOakland University · US

Funding

MicroRNAs and neurogenesis after strokeR01NS075156 · NINDS · HENRY FORD HEALTH SYSTEM · PI ZHANG, ZHENG GANG · 2011 to 2015
$1.6M
MSCs Induce Brain Plasticity via tPAR01AG037506 · NIA · HENRY FORD HEALTH SYSTEM · PI CHOPP, MICHAEL · 2011 to 2015
$1.5M
RADIANCE 2100 AG-2Q CONFOCAL SYSTEM: STROKE, BRAIN TUMORS10RR019245 · NCRR · HENRY FORD HEALTH SYSTEM · PI ZHANG, ZHENG GANG · 2005 to 2005
$500k
NCRR NIH HHS S10 RR019245NIA NIH HHS R01 AG037506NINDS NIH HHS R01 NS075156
6 · The paper itself

Abstract

Cerebral ischemia induces neurogenesis, including proliferation and differentiation of neural progenitor cells and migration of newly generated neuroblasts. MicroRNAs (miRNAs) are small noncoding RNAs that decrease gene expression through mRNA destabilization and/or translational repression. Emerging data indicate that miRNAs have a role in mediating processes of proliferation and differentiation of adult neural progenitor cells. This article reviews recent findings on miRNA profile changes in neural progenitor cells after cerebral infarction and the contributions of miRNAs to their ischemia-induced proliferation and differentiation. We highlight interactions between the miR-124 and the miR17-92 cluster and the Notch and Sonic hedgehog signaling pathways in mediating stroke-induced neurogenesis.

Indexed as

AnimalsBrain IschemiaCell MovementHumansMicroRNAsNeural Stem CellsNeurogenesisSignal TransductionMicroRNAs

Identifiers

PMID23860031
PMCPMC3746334
OpenAlexW2060186714

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.