ArticleAlimentary pharmacology & therapeutics2013
The incidence of acute pancreatitis: impact of social deprivation, alcohol consumption, seasonal and demographic factors.
Article in Alimentary pharmacology & therapeutics, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 97 papers, 7 of them syntheses that pooled it.
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Who cites it
97 citing papers in PubMed, 7 syntheses or guidelines pooled it.
- Global burden and characterization of hypertriglyceridemia-induced acute pancreatitis: results from a systematic review and a multi-center cohort study.Science China. Life sciences · 2025Pooled it
- Neostigmine for non-mild acute pancreatitis: A systematic review and meta-analysis of randomized controlled trials.Frontiers in pharmacology · 2023Pooled it
- Causal mechanisms proposed for the alcohol harm paradox-a systematic review.Addiction (Abingdon, England) · 2022Pooled it
- Pharmacological interventions for acute pancreatitis.The Cochrane database of systematic reviews · 2017Pooled it
- Serum C-reactive protein, procalcitonin, and lactate dehydrogenase for the diagnosis of pancreatic necrosis.The Cochrane database of systematic reviews · 2017Pooled it
- Serum amylase and lipase and urinary trypsinogen and amylase for diagnosis of acute pancreatitis.The Cochrane database of systematic reviews · 2017Pooled it
- Interventions for necrotising pancreatitis.The Cochrane database of systematic reviews · 2016Pooled it
- Article
- Clinical Epidemiology and Burden of Acute and Chronic Pancreatitis in Chinese Children: A Nationwide Study.Digestive diseases and sciences · 2026Article
- Severe adverse clinical impacts are predicted by an early high positive fluid balance in patients with severe acute pancreatitis.Scientific reports · 2026Article
- Regional and Sex-Specific Trends in the Burden of Pancreatitis in Asia, 1990-2021: A Global Burden of Disease Study 2021 Analysis.International journal of women's health · 2026Article
- Phosphate Improves Mitochondrial Function and Reduces Pancreatitis in Hypertriglyceridemia.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2025Article
- Comprehensive statistical analysis of serum interleukin-6 and C-reactive protein for early diagnosis of severe acute pancreatitis: A systematic review and meta-analysis.Journal of family medicine and primary care · 2025Article
- Outcomes of Acute Pancreatitis Hospitalizations with Obesity.Digestive diseases and sciences · 2025Article
- Global, regional, and national burden of pancreatitis in children and adolescents.United European gastroenterology journal · 2025Article
- Diagnostic accuracy of interleukin-6 as a biomarker for early prediction of severe acute pancreatitis: A systematic review and meta-analysis.Journal of family medicine and primary care · 2025Article
- Diagnosis and Management of Acute Pancreatitis.Diagnostics (Basel, Switzerland) · 2025Review
- Developing a Core Outcome Set for blood purification in hypertriglyceridemic acute pancreatitis: a Delphi study protocol.Frontiers in medicine · 2025Article
- Mucus and mucin: changes in the mucus barrier in disease states.Tissue barriers · 2025Review
- Comparative analysis of trends in the burden of pancreatitis in China and worldwide, 1990-2021.Frontiers in public health · 2025Article
37 more citing papers are in PubMed but not listed here.
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5 authors.
Funding
Abstract
backgroundThe incidence of acute pancreatitis has increased sharply in many European countries and the USA in recent years.
aimTo establish trends in incidence and mortality for acute pancreatitis in Wales, UK, and to assess how incidence may be linked to factors including social deprivation, seasonal effects and alcohol consumption.
methodsUse of record linked inpatient, mortality and primary care data for 10,589 hospitalised cases of acute pancreatitis between 1999 and 2010.
resultsThe incidence of acute pancreatitis was 30.0 per 100,000 population overall, mortality was 6.4% at 60 days. Incidence increased significantly from 27.6 per 100,000 in 1999 to 36.4 in 2010 (average annual increase = 2.7% per year), there was little trend in mortality (0.2% average annual reduction). The largest increases in incidence were among women aged <35 years (7.9% per year) and men aged 35-44 (5.7%) and 45-54 (5.3%). Incidence was 1.9 times higher among the most deprived quintile of patients compared with the most affluent (3.9 times higher for alcoholic acute pancreatitis and 1.5 for gallstone acute pancreatitis). Acute pancreatitis was increased significantly during the Christmas and New Year weeks by 48% (95% CI = 24-77%) for alcoholic aetiology, but not for gallstone aetiology (9%). Alcoholic admissions were increased with higher consumption of spirits and beer, but not wine.
conclusionsThe study shows an elevated rate of alcoholic acute pancreatitis during the Christmas and New Year period. Acute pancreatitis continues to rise, most rapidly for young women, while alcoholic acute pancreatitis is linked strongly with social deprivation.
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