Evidence map›Paper›PMID 23859218›Full record

ArticleOrganic letters2013

Synthesis of 6-Se-guanosine RNAs for structural study.

Jozef Salon, Jianhua Gan, Rob Abdur, Hehua Liu, Zhen Huang

Abstract read
In one paragraph

Article in Organic letters, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
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  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Jozef SalonDepartment of Chemistry, Georgia State University, Atlanta, Georgia 30303, USA.
Jianhua Gan
Rob Abdur
Hehua Liu
Zhen Huang

Funding

Selenium-Derivatized RNAs and DNAs for High-Throughput Protein/Nucleic Acid CrystR01GM095881 · NIGMS · GEORGIA STATE UNIVERSITY · PI HUANG, ZHEN · 2012 to 2016
$1.4M
NIGMS NIH HHS R01 GM095881NIGMS NIH HHS R01GM095881
6 · The paper itself

Abstract

6-Se-guanosine phosphoramidite and RNAs have been synthesized by selenium substitution of the 6-oxygen atom, and it is revealed that the Se-derivatization is relatively stable and that bulge and wobble structures can better accommodate a large Se atom than a duplex. This Se-modification is useful in the structural study of RNAs and their protein complexes.

Indexed as

Crystallography, X-RayGuanosineMolecular StructureNucleic Acid ConformationOrganoselenium CompoundsRNASeleniumGuanosineOrganoselenium CompoundsRNASelenium

Identifiers

PMID23859218
PMCPMC3763942

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.