Evidence map›Paper›PMID 23858620›Full record

ReviewPediatric endocrinology reviews : PER2013

The changing face of hypophosphatemic disorders in the FGF-23 era.

Janet Y Lee, Erik A Imel

Abstract readCase ReportsReview
In one paragraph

Review in Pediatric endocrinology reviews : PER, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
1.6field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it, 26 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Burden of disease and clinical targets in adult patients with X-linked hypophosphatemia. A comprehensive review.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2021
    Review
  5. Article
  6. Article
  7. [Dental-craniofacial manifestation and treatment of rare diseases in China].Hua xi kou qiang yi xue za zhi = Huaxi kouqiang yixue zazhi = West China journal of stomatology · 2019
    Article
  8. Dental-craniofacial manifestation and treatment of rare diseases.International journal of oral science · 2019
    Review
  9. Article
  10. FGF23 Neutralizing Antibody Partially Improves Bone Mineralization Defect of HMWFGF2 Isoforms in Transgenic Female Mice.Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2018
    Article
  11. Article
  12. Article
  13. [Diagnostics in osteology].Der Internist · 2016
    Review
  14. Article
  15. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Janet Y LeeDepartment of Medicine, Indiana University School of Medicine, Indianapolis, IN, USA.
Erik A Imel
Indiana University School of Medicine

Funding

FGF23 in Pediatric Phosphate Physiology and X-linked Hypophosphatemic Rickets.K23AR057096 · NIAMS · INDIANA UNIVERSITY INDIANAPOLIS · PI IMEL, ERIK ALLEN · 2009 to 2013
$642k
NIAMS NIH HHS K23 AR057096
6 · The paper itself

Abstract

In the past decade, research in genetic disorders of hypophosphatemia has significantly expanded our understanding of phosphate metabolism. X-linked hypophosphatemia (XLH) is the most common inherited form of rickets due to renal phosphate wasting. Recent understanding of the mechanisms of disease and role of fibroblast growth factor 23 (FGF-23) in XLH and other hypophosphatemic disorders have opened new potential therapeutic avenues. We will discuss the current standard of treatment for XLH as well as promising future directions under study.

Indexed as

Genetic Diseases, X-LinkedFamilial Hypophosphatemic RicketsFemaleFibroblast Growth Factor-23Fibroblast Growth FactorsHumansInfantPhosphatesFGF23 protein, humanFibroblast Growth Factor-23Fibroblast Growth FactorsPhosphates

Identifiers

PMID23858620
PMCPMC4170520
OpenAlexW101796757

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.