Evidence map›Paper›PMID 23858374›Full record

ArticleWorld journal of gastrointestinal endoscopy2013

Endoscopic treatments for chronic radiation proctitis.

George Karamanolis, Panagiota Psatha, Konstantinos Triantafyllou

Open access · hybridAbstract read
In one paragraph

Article in World journal of gastrointestinal endoscopy, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
3.4field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 24 citations in OpenAlex.

  1. A Randomized Controlled Trial of Novel Treatment for Hemorrhagic Radiation Proctitis.Asian Pacific journal of cancer prevention : APJCP · 2020
    Trial
  2. The role of hyperbaric oxygen therapy in the treatment of radiation lesions.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2022
    Article
  3. Review
  4. Article
  5. Chronic haemorrhagic radiation proctitis: A review.World journal of gastrointestinal surgery · 2016
    Review
  6. Article
  7. Review
  8. Article
  9. Radiation proctitis as a differential of lower GIT bleeding in Nigeria: A case series.Nigerian medical journal : journal of the Nigeria Medical Association
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

George KaramanolisGeorge Karamanolis, Gastroenterology Unit, 2 Department of Surgery, "Aretaieio" University Hospital, Athens University, 11528 Athens, Greece.
Panagiota Psatha
Konstantinos Triantafyllou
Aretaeio Hospital · GR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chronic radiation proctitis is a complication that occurs in patients who receive radiation therapy for pelvic malignancies. The common presentation is with rectal bleeding, but also rectal pain, diarrhea, tenesmus and even passage of mucus can occur. The optimal treatment of bleeding due to radiation proctitis remains unclear. Among various therapeutic options, medical management is generally ineffective and surgical intervention has a high incidence of morbidity. Promising advances have been made in endoscopic therapy, including argon plasma coagulation (APC), formalin application as well as new techniques such as radiofrequency ablation and cryoablation. APC is a safe, highly effective and long-lasting therapy in patients with rectal bleeding associated with radiation proctitis. It has been shown that several sessions of APC reduce the rate of bleeding and therefore the blood transfusion requirements. Moreover, the effect of treatment is long lasting. However, best results are achieved in patients with mild to moderate radiation proctitis, leaving space for alternative treatments for patients with more severe disease. In patients with severe or refractory radiation proctitis intra rectal formalin application is an appropriate treatment option. Radiofrequency ablation and cryoablation have shown efficacy as alternative methods in a limited number of patients with refractory chronic radiation proctitis.

Indexed as

Argon plasma coagulationCryoablationEndoscopic treatmentFormalin applicationRadiation proctitisRadiofrequency ablation

Identifiers

PMID23858374
PMCPMC3711061
OpenAlexW2090153306

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.