ReviewWiley interdisciplinary reviews. Systems biology and medicine
Endothelial cell motility, coordination and pattern formation during vasculogenesis.
Review in Wiley interdisciplinary reviews. Systems biology and medicine. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
15 citing papers in PubMed, 40 citations in OpenAlex.
- Scaffold-mediated miRNA-155 inhibition promotes regenerative macrophage polarisation leading to anti-inflammatory, angiogenic and neurogenic responses for wound healing.Bioactive materials · 2026Article
- Fast yet force-effective mode of supracellular collective cell migration due to extracellular force transmission.PLoS computational biology · 2025Article
- Effects of polylactic acid scaffolds with various orientations and diameters on osteogenesis and angiogenesis.Frontiers in bioengineering and biotechnology · 2024Article
- A three-dimensional model with two-body interactions for endothelial cells in angiogenesis.Scientific reports · 2023Article
- Article
- Integrative experimental/computational approach establishes active cellular protrusion as the primary driving force of phagocytic spreading by immune cells.PLoS computational biology · 2022Article
- Directing Multicellular Organization by Varying the Aspect Ratio of Soft Hydrogel Microwells.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2022Article
- Characterization of Integrin Molecular Tension of Human Breast Cancer Cells on Anisotropic Nanopatterns.Frontiers in molecular biosciences · 2022Article
- Roles of Remote and Contact Forces in Epithelial Cell Structure Formation.Biophysical journal · 2020Article
- Enhanced endothelial motility and multicellular sprouting is mediated by the scaffold protein TKS4.Scientific reports · 2019Article
- Neural crest streaming as an emergent property of tissue interactions during morphogenesis.PLoS computational biology · 2019Article
- Soluble VEGFR1 signaling guides vascular patterns into dense branching morphologies.Journal of theoretical biology · 2018Article
- Anisotropic forces from spatially constrained focal adhesions mediate contact guidance directed cell migration.Nature communications · 2017Article
- A Network Model to Explore the Effect of the Micro-environment on Endothelial Cell Behavior during Angiogenesis.Frontiers in physiology · 2017Article
- Tip cell overtaking occurs as a side effect of sprouting in computational models of angiogenesis.BMC systems biology · 2015Article
Corrections and comments
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Authors and funding
1 author at 1 institution in 2 countries.
Funding
Abstract
How vascular networks assemble is a fundamental problem of developmental biology that also has medical importance. To explain the organizational principles behind vascular patterning, we must understand how can tissue level structures be controlled through cell behavior patterns like motility and adhesion that, in turn, are determined by biochemical signal transduction processes? We discuss the various ideas that have been proposed as mechanisms for vascular network assembly: cell motility guided by extracellular matrix alignment (contact guidance), chemotaxis guided by paracrine and autocrine morphogens, and multicellular sprouting guided by cell-cell contacts. All of these processes yield emergent patterns, thus endothelial cells can form an interconnected structure autonomously, without guidance from an external pre-pattern.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.