ArticleInternational journal of colorectal disease2014
Long-term outcome of laparoscopic ileocecal resection for Crohn's disease before the era of biologics.
Article in International journal of colorectal disease, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 3 of them syntheses that pooled it.
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Who cites it
9 citing papers in PubMed, 3 syntheses or guidelines pooled it, 14 citations in OpenAlex.
- Incidence and predictors of surgical recurrence after primary ileocolic resection in Crohn ileitis: a systematic review and meta-analysis.Inflammatory bowel diseases · 2026Pooled it
- Management of ileocolic anastomotic strictures in Crohn's disease: endoscopic or surgical intervention? A systematic review and meta-analysis.International journal of colorectal disease · 2025Pooled it
- Disease recurrence in patients with Crohn's disease after biologic therapy or surgery: a meta-analysis.International journal of colorectal disease · 2022Pooled it
- Primary surgery versus pharmacotherapy for newly diagnosed ileocecal Crohn's disease: a hospital-based cohort study.The Korean journal of internal medicine · 2024Article
- Laparoscopy Combined with Enhanced Recovery Pathway in Ileocecal Resection for Crohn's Disease: A Randomized Study.Gastroenterology research and practice · 2018Article
- Laparoscopic surgery in the management of Crohn's disease.World journal of gastrointestinal pathophysiology · 2014Review
- [Operative therapy of chronic inflammatory bowel diseases. Indications and importance].Der Internist · 2014Review
- Therapy of complicated Crohn's disease during pregnancy--an interdisciplinary challenge.International journal of colorectal disease · 2014Review
- [Refractory inflammatory bowel disease: surgical challenges].Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen · 2013Review
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundCrohn's disease (CD) of the terminal ileum not responding to standard medical treatment is more and more treated with biologics instead of surgery. In order to get more information on the results of surgery, we analyzed the outcome of laparoscopic ileocecal resection (LICR) performed before the widespread use of these drugs.
methodsChart reviews and telephone follow-ups were performed on 119 patients treated with laparoscopic ileocecal resection for CD. Follow-ups were performed at a median of 58 (17-124) and 113(69-164) months. Symptomatic restenosis requiring surgery or endoscopic dilatation was the primary endpoint. We further analyzed risk factors of recurrence.
resultsOf the 119 patients initially treated, 18 required surgery (n = 14) or endoscopic dilatation (n = 4). The calculated rates of re-intervention were 10 und 17.5 % at 5 and 10 years, respectively. Ninety percent of the patients had a Crohn-specific medication treatment at the time of surgery, but only 51.4 und 46.9 % at FU 1 und 2, respectively. Smoking increased the risk of recurrence (OR 3.7, P = 0.011).
conclusionThe data demonstrate excellent long-term results of LICR for CD of the terminal ileum. Surgery should be considered as a first choice treatment in many patients with ileocecal CD not responding to conventional treatment.
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