Evidence map›Paper›PMID 23857549›Full record

ReviewDrugs2013

Management of neurogenic orthostatic hypotension in patients with autonomic failure.

Christoph Schroeder, Jens Jordan, Horacio Kaufmann

Abstract readReview
PubMed Publisher
In one paragraph

Review in Drugs, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
4.6field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it, 29 citations in OpenAlex.

  1. Pooled it
  2. Efficacy of atomoxetine versus midodrine for neurogenic orthostatic hypotension.Annals of clinical and translational neurology · 2020
    Trial
  3. Review
  4. Cardiovascular autonomic nervous system responses and orthostatic intolerance in astronauts and their relevance in daily medicine.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2022
    Review
  5. Dysautonomia: A Forgotten Condition - Part II.Arquivos brasileiros de cardiologia · 2021
    Article
  6. Syncope and Headache.Current pain and headache reports · 2018
    Review
  7. Review
  8. Pure Autonomic Failure.Current neurology and neuroscience reports · 2016
    Review
  9. Supine hypertension in Parkinson's disease and multiple system atrophy.Clinical autonomic research : official journal of the Clinical Autonomic Research Society · 2016
    Article
  10. Drug therapies in older adults (part 2).Clinical medicine (London, England) · 2015
    Review
  11. Multiple system atrophy: using clinical pharmacology to reveal pathophysiology.Clinical autonomic research : official journal of the Clinical Autonomic Research Society · 2015
    Article
  12. Review
  13. Droxidopa in neurogenic orthostatic hypotension.Expert review of cardiovascular therapy · 2015
    Article
  14. Review
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

Christoph SchroederInstitute of Clinical Pharmacology, OE 5350, Hannover Medical School, Carl-Neuberg-Strasse 1, 30625, Germany. schroeder.christoph@mh-hannover.de
Jens Jordan
Horacio Kaufmann
Medizinische Hochschule Hannover · DEDysautonomia Foundation · US

Funding

Intramural NIH HHS
6 · The paper itself

Abstract

The maintenance of blood pressure in the upright position requires intact autonomic cardiovascular reflexes. Diseases that affect the sympathetic innervation of the cardiovascular system result in a sustained fall in blood pressure upon standing (i.e., neurogenic orthostatic hypotension) that can impair the blood supply to the brain and other organs and cause considerable morbidity and mortality. Here we review treatment options for neurogenic orthostatic hypotension and include an algorithm for its management that emphasizes the importance of non-pharmacologic measures and provides guidance on pharmacologic treatment options.

Indexed as

AlgorithmsAutonomic Nervous System DiseasesBlood PressureHumansHypotension, OrthostaticPostureWaterWater

Identifiers

PMID23857549
OpenAlexW1987889517

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.