ReviewMolecular neurobiology2014
Exosomes: a new weapon to treat the central nervous system.
Review in Molecular neurobiology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
31 citing papers in PubMed.
- Construction of Smart Hydrogel-Exosome Drug Delivery Platforms and Their Applications in Skin Rehabilitation.International journal of nanomedicine · 2026Review
- Integrins from extracellular vesicles as players in tumor microenvironment and metastasis.Cancer metastasis reviews · 2025Review
- K-562 Extracellular Vesicles Partially Protect Intact Cells from Oxidative Stress and Provide Limited Resistance to Imatinib.Current issues in molecular biology · 2025Article
- MicroRNA Cargo in Wharton's Jelly MSC Small Extracellular Vesicles: Key Functionality to In Vitro Prevention and Treatment of Premature White Matter Injury.Stem cell reviews and reports · 2023Article
- Global Research Trends of Exosomes in the Central Nervous System: A Bibliometric and Visualized Analysis.Neurospine · 2023Article
- Exosomes as New Generation Vehicles for Drug Delivery: Biomedical Applications and Future Perspectives.Molecules (Basel, Switzerland) · 2022Review
- Microglia Polarization: A Novel Target of Exosome for Stroke Treatment.Frontiers in cell and developmental biology · 2022Review
- Zeb2/Axin2-Enriched BMSC-Derived Exosomes Promote Post-Stroke Functional Recovery by Enhancing Neurogenesis and Neural Plasticity.Journal of molecular neuroscience : MN · 2022Article
- Schwann cells-derived exosomes promote functional recovery after spinal cord injury by promoting angiogenesis.Frontiers in cellular neuroscience · 2022Article
- Exosomes in Alzheimer's Disease: From Being Pathological Players to Potential Diagnostics and Therapeutics.International journal of molecular sciences · 2021Review
- Stem Cell Extracellular Vesicles and their Potential to Contribute to the Repair of Damaged CNS Cells.Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology · 2020Article
- The role of exosomes in stroke.Molecular biology reports · 2020Review
- Cell Secretome: Basic Insights and Therapeutic Opportunities for CNS Disorders.Pharmaceuticals (Basel, Switzerland) · 2020Review
- RNA cargos in extracellular vesicles derived from blood serum in pancreas associated conditions.Scientific reports · 2020Article
- MiR-124 Enriched Exosomes Promoted the M2 Polarization of Microglia and Enhanced Hippocampus Neurogenesis After Traumatic Brain Injury by Inhibiting TLR4 Pathway.Neurochemical research · 2019Article
- Therapeutic Potential of Extracellular Vesicles for the Treatment of Nerve Disorders.Frontiers in neuroscience · 2019Review
- Recent advancements in the use of exosomes as drug delivery systems.Journal of nanobiotechnology · 2018Review
- Extracellular vesicles: the growth as diagnostics and therapeutics; a survey.Journal of extracellular vesicles · 2018Review
- Intranasal administration of exosomes derived from mesenchymal stem cells ameliorates autistic-like behaviors of BTBR mice.Molecular autism · 2018Article
- [Research advances in mesenchymal stem cell-derived exosomes in treatment of brain injury].Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2017Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The potential of exosomes to treat central nervous system (CNS) pathologies has been recently demonstrated. These studies make way for a complete new field that aims to exploit the natural characteristics of these vesicles, considered for a long time as side products of physiological cellular pathways. Recently, however, the biological significance of exosomes has been evaluated and exosomes can now be viewed upon as new relevant functional entities for development of novel therapeutic strategies. In this review, we aim to summarize the state-of-the-art role of exosomes in the CNS and to speculate about possible future therapeutic applications of exosomes. In particular, we will speculate about the use of these vesicles as a substitute of cell-based therapies for the treatment of brain damage and review the potential of exosomes as drug delivery vehicles for the CNS.
Indexed as
Identifiers
23857502What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.