Evidence map›Paper›PMID 23857353›Full record

ArticlePlant signaling & behavior2013

Signal integration on plant promoters: a case study in maize.

Ina Horst, Louisa Heimann, Christoph Peterhansel

Open access · hybridAbstract read
In one paragraph

Article in Plant signaling & behavior, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.9field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Ina HorstLeibniz University Hannover; Institute of Botany; Hannover, Germany; These authors contributed equally to this work.
Louisa Heimann
Christoph Peterhansel
Leibniz University Hannover · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Gene promoters perceive numerous signals and integrate this information into a single response, the transcriptional activity of a gene. It was speculated that covalent modification of histones on the promoters might have an important function in storage and integration of signals. Using the genes for the core proteins of C4 metabolism in maize as a model, we associated the perception of specific signals with the establishment of individual histone modifications. Core elements of the histone code defined in these studies are conserved on all C4 genes and on other maize genes that respond to similar stimuli. Moreover, the code is used in independent C4 lineages. However, our data also advise caution because interpretation of histone modifications might differ dependent on the promoter position of the modification. The model provided here constitutes a starting point for genome-wide decoding of stimulus-modification pairs in epigenetic gene regulation.

Indexed as

Promoter Regions, GeneticAcetylationGene Expression Regulation, PlantGenes, PlantHistonesLightMethylationPhylogenyProtein Processing, Post-TranslationalSignal TransductionZea maysHistonesC4 photosynthesishistone codehistone modificationSetaria italicasignal integrationSorghum bicolorZea mays

Identifiers

PMID23857353
PMCPMC4002602
OpenAlexW2066236176

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.