Evidence map›Paper›PMID 23857036›Full record

Trial reportInternal and emergency medicine2014

Effect of High-Intensity interval training versus moderate continuous training on 24-h blood pressure profile and insulin resistance in patients with chronic heart failure.

Ferdinando Iellamo, Giuseppe Caminiti, Barbara Sposato, Cristiana Vitale, Michele Massaro, Giuseppe Rosano, Maurizio Volterrani

Abstract readComparative StudyRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in Internal and emergency medicine, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 13 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed, 13 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 13 syntheses or guidelines pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Ferdinando IellamoIstituto di Ricovero e Cura a Carattere Scientifico San Raffaele Pisana, Rome, Italy, iellamo@med.uniroma2.it.
Giuseppe Caminiti
Barbara Sposato
Cristiana Vitale
Michele Massaro
Giuseppe Rosano
Maurizio Volterrani

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In patients with chronic heart failure (CHF) blood pressure (BP) control, represents a relevant target of management. This study evaluated the effect of different intensities exercise training on 24-h ambulatory BP profile and insulin resistance in patients with CHF. Thirty-six CHF patients with left ventricular ejection fraction <40%, were randomized to high-intensity interval training (HIT) or moderate continuous training (MIT) for 12 weeks. HIT consisted in treadmill exercise at ~75-80% of heart rate reserve (HRR), alternated with active pauses at 45-50% of HRR. MIT consisted in continuous treadmill at ~45-60% of HRR. Peak VO2 and anaerobic threshold increased significantly with both HIT and MIT, without significant differences between the two training programs. 24-h, systolic and diastolic BP decreased with both HIT and MIT. The same occurred for day-time and night-time systolic and diastolic BP. The decrease in day-time diastolic BP was slightly but significantly greater in HIT. Both HIT and MIT induced a significant decrease in fasting glucose and insulin, whereas HOMA-IR decreased significantly only after HIT. In patients with CHF exercise training reduces BP throughout the day, without substantial differences between moderate and more vigorous exercise intensity, with a small exception for day-time diastolic BP. HIT was more effective in improving insulin resistance.

Indexed as

Blood PressureExerciseInsulin ResistanceAgedBlood Pressure Monitoring, AmbulatoryChronic DiseaseFemaleHeart FailureHumansMale

Identifiers

PMID23857036

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.