ArticleJournal of the American Geriatrics Society2013
Objective measures of physical activity, fractures and falls: the osteoporotic fractures in men study.
Article in Journal of the American Geriatrics Society, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers, 5 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
40 citing papers in PubMed, 5 syntheses or guidelines pooled it.
- Physical activity for prevention of cardiovascular disease: consensus statement of Korean Society of Cardio-cerebrovascular Disease Prevention.The Korean journal of internal medicine · 2025Guideline
- The association between sedentary behavior and falls in older adults: A systematic review and meta-analysis.Frontiers in public health · 2022Pooled it
- Sarcopenia Definitions as Predictors of Fracture Risk Independent of FRAXJournal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2021Pooled it
- Physical Activity, Injurious Falls, and Physical Function in Aging: An Umbrella Review.Medicine and science in sports and exercise · 2019Pooled it
- Measures of Physical Performance and Muscle Strength as Predictors of Fracture Risk Independent of FRAX, Falls, and aBMD: A Meta-Analysis of the Osteoporotic Fractures in Men (MrOS) Study.Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2018Pooled it
- VITamin D and OmegA-3 TriaL (VITAL): Effects of Vitamin D Supplements on Risk of Falls in the US Population.The Journal of clinical endocrinology and metabolism · 2020Trial
- Risk Factors for Hip Fracture in Older Men: The Osteoporotic Fractures in Men Study (MrOS).Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2016Trial
- The Osteoporotic Fractures in Men study (MrOS): a 25-yr landmark study of skeletal health in older men.Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2026Article
- Associations of Accelerometer-Measured Physical Activity and Sedentary Behavior With Incident Clinical Osteoporotic Fractures Among Older Women: The Objective Physical Activity and Cardiovascular Health Study.Journal of aging and physical activity · 2026Article
- 24-hour activity composition is associated with lower fall and fracture risk in older men.Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2024Article
- Physical Activity Fragmentation and Falls in Older Adults: Findings From the National Health and Aging Trends Study.The journals of gerontology. Series A, Biological sciences and medical sciences · 2024Article
- Sedentary behavior does not predict low BMD nor fracture-population-based Canadian Multicentre Osteoporosis Study.Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2024Article
- Breaking Up Sedentary Time Reduces Recurrent Fall Risk, but Not Incident Fracture Risk in Older Men.JBMR plus · 2023Article
- Rationale and design of an ancillary study evaluating the effects of the cocoa flavanol and/or multivitamin interventions on falls and physical performance outcomes in the COcoa Supplement and Multivitamin Outcomes Study (COSMOS).Contemporary clinical trials · 2023Article
- Objective and Self-Reported Physical Activity and Risk of Falling Among Community-Dwelling Older Adults From Southern Brazil.Journal of aging and physical activity · 2022Article
- Utilizing nomograms to predict prevalent vertebral fracture risk: An analysis of dysmobility syndrome in a community-dwelling population.Biomedical journal · 2022Article
- Male osteoporosis.Archives of endocrinology and metabolism · 2022Review
- Accelerometer-Measured Daily Steps, Physical Function, and Subsequent Fall Risk in Older Women: The Objective Physical Activity and Cardiovascular Disease in Older Women Study.Journal of aging and physical activity · 2022Article
- Association Between Muscle Mass Determined by DJournal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2022Article
- Association between physical activity and falls among older adults in rural China: are there gender and age related differences?BMC public health · 2022Article
Corrections and comments
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Authors and funding
7 authors.
Funding
Abstract
objectivesTo determine the association between objectively measured physical activity (PA), fractures, and falls.
designLongitudinal cohort study.
settingSix U.S. clinical sites.
participantsTwo thousand seven hundred thirty-one men with a mean age of 79. MEASUREMENTS: Total and active energy expenditure (EE) and minutes per day spent in sedentary and moderate intensity activities were measured for at least 5 days. Energy expended at a metabolic equivalent of greater than three was termed active EE. Incident nonspine fractures and falls were identified every 4 months.
resultsSeven hundred fifty-nine (28.2%) men fell at least once over 12 months of follow-up; 186 (6.8%) experienced one or more fractures over an average follow-up of 3.5 ± 0.9 years. The association between PA and falling varied according to age (P interaction = .02). Men younger than 80 with the lowest active EE had a lower risk of falling than men with the highest active EE (relative risk (RR) = 0.75; P trend = .08), whereas men aged 80 and older with the lowest active EE had a higher risk of falling than men with the highest active EE (RR = 1.43, P trend = .09). In multivariate models including health status, men in the lowest quintile of active EE had a significantly higher risk of fracture (hazard ratio (HR) = 1.82, 95% confidence interval (CI) = 1.10-3.00, P trend = .04) than men in highest quintile. Men with <33 min/d of moderate activity had a 70% greater risk of fracture (HR = 1.70, 95% CI = 1.03-2.80).
conclusionAge modifies the association between PA and falling. Interventions aimed at obtaining more than 30 minutes of moderate PA per day may reduce fractures, extending PA guidelines to the oldest old, the fastest-growing proportion of those aged 65 and older.
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