ArticleNeuroImage. Clinical2013
Reorganisation of brain networks in frontotemporal dementia and progressive supranuclear palsy.
Article in NeuroImage. Clinical, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
29 citing papers in PubMed, 1 synthesis or guideline pooled it, 61 citations in OpenAlex.
- Characterisation of meta-analytical functional connectivity in progressive supranuclear palsy.Clinical radiology · 2018Pooled it
- GABA-ergic Dynamics in Human Frontotemporal Networks Confirmed by Pharmaco-Magnetoencephalography.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2020Trial
- Improving response inhibition systems in frontotemporal dementia with citalopram.Brain : a journal of neurology · 2015Trial
- Alzheimer's disease and memantine effects on NMDA-receptor blockade: non-invasive in vivo insights from magnetoencephalography.Molecular psychiatry · 2026Article
- Alzheimer's disease and its progression reduce pyramidal cell gain and connectivity.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025Article
- GABAergic modulation of beta power enhances motor adaptation in frontotemporal lobar degeneration.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025Article
- Frontotemporal lobar degeneration changes neuronal beta-frequency dynamics during the mismatch negativity response.NeuroImage. Clinical · 2024Article
- A multimodal cortical network of sensory expectation violation revealed by fMRI.Human brain mapping · 2023Article
- Neurophysiological consequences of synapse loss in progressive supranuclear palsy.Brain : a journal of neurology · 2023Article
- Shared brain transcriptomic signature in TDP-43 type A FTLD patients with or without GRN mutations.Brain : a journal of neurology · 2022Article
- In vivo coupling of dendritic complexity with presynaptic density in primary tauopathies.Neurobiology of aging · 2021Article
- Neurocognitive disorders in the elderly: altered functional resting-state hyperconnectivities in postoperative delirium patients.Translational psychiatry · 2021Observational
- In Vivo Assay of Cortical Microcircuitry in Frontotemporal Dementia: A Platform for Experimental Medicine Studies.Cerebral cortex (New York, N.Y. : 1991) · 2021Article
- Decoding expectation and surprise in dementia: the paradigm of music.Brain communications · 2021Article
- A Critical Review of Alien Limb-Related Phenomena and Implications for Functional Magnetic Resonance Imaging Studies.Frontiers in neurology · 2021Review
- Alien limb syndrome: A Bayesian account of unwanted actions.Cortex; a journal devoted to the study of the nervous system and behavior · 2020Review
- Anterior temporal lobe is necessary for efficient lateralised processing of spoken word identity.Cortex; a journal devoted to the study of the nervous system and behavior · 2020Article
- Biomagnetic biomarkers for dementia: A pilot multicentre study with a recommended methodological framework for magnetoencephalography.Alzheimer's & dementia (Amsterdam, Netherlands) · 2019Article
- Neurophysiological signatures of Alzheimer's disease and frontotemporal lobar degeneration: pathology versus phenotype.Brain : a journal of neurology · 2018Article
- Neurotransmitter deficits from frontotemporal lobar degeneration.Brain : a journal of neurology · 2018Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 3 institutions in 1 country.
Funding
Abstract
The disruption of large-scale brain networks is increasingly recognised as a consequence of neurodegenerative dementias. We assessed adults with behavioural variant frontotemporal dementia and progressive supranuclear palsy using magnetoencephalography during an auditory oddball paradigm. Network connectivity among bilateral temporal, frontal and parietal sources was examined using dynamic causal modelling. We found evidence for a systematic change in effective connectivity in both diseases. Compared with healthy subjects, who had focal modulation of intrahemispheric frontal-temporal connections, the patient groups showed abnormally extensive and inefficient networks. The changes in connectivity were accompanied by impaired responses of the auditory cortex to unexpected deviant tones (MMNm), despite normal responses to standard stimuli. Together, these results suggest that neurodegeneration in two distinct clinical syndromes with overlapping profiles of prefrontal atrophy, causes a similar pattern of reorganisation of large-scale networks. We discuss this network reorganisation in the context of other focal brain disorders and the specific vulnerability of functional brain networks to neurodegenerative disease.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.