ArticleJournal of global infectious diseases2013
Multiplex PCR for rapid diagnosis of gastrointestinal tuberculosis.
Article in Journal of global infectious diseases, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 3 of them syntheses that pooled it.
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Who cites it
12 citing papers in PubMed, 3 syntheses or guidelines pooled it, 36 citations in OpenAlex.
- Meta-analysis of diagnostic accuracy of nucleic acid amplification tests for abdominal tuberculosis.PloS one · 2023Pooled it
- Diagnostic accuracy of the loop-mediated isothermal amplification assay for extrapulmonary tuberculosis: A meta-analysis.PloS one · 2018Pooled it
- Gastrointestinal tuberculosis: A systematic review of epidemiology, presentation, diagnosis and treatment.Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology AssociationPooled it
- Obstructive jaundice caused by an abdominal tuberculous mass lesion.Clinical journal of gastroenterology · 2025Article
- Tuberculosis of abdominal lymph nodes, peritoneum, and GI tract: a malignancy mimic.Abdominal radiology (New York) · 2022Review
- Recent advances in the diagnosis of intestinal tuberculosis.BMC gastroenterology · 2022Review
- Multiplex Polymerase Chain Reaction for diagnosis of gastrointestinal tuberculosis.JGH open : an open access journal of gastroenterology and hepatology · 2019Article
- RNomic identification and evaluation of npcTB_6715, a non-protein-coding RNA gene as a potential biomarker for the detection of Mycobacterium tuberculosis.Journal of cellular and molecular medicine · 2017Article
- Comparative Study of GeneXpert MTB/RIF Assay and Multiplex PCR Assay for Direct Detection of Mycobacterium tuberculosis in Suspected Pulmonary Tuberculosis Patients.Current microbiology · 2017Article
- Comparative Evaluation of Several Gene Targets for Designing a Multiplex-PCR for an Early Diagnosis of Extrapulmonary Tuberculosis.Yonsei medical journal · 2016Article
- Abdominal tuberculosis of the gastrointestinal tract: revisited.World journal of gastroenterology · 2014Review
- Utility of tissue Xpert-Mtb/Rif for the diagnosis of intestinal tuberculosis in patients with ileocolonic ulcers.Therapeutic advances in infectious diseaseArticle
Corrections and comments
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Authors and funding
9 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundRapid and specific diagnosis of gastrointestinal tuberculosis (GITB) is of utmost importance.
aimTo evaluate Multiplex PCR (MPCR) using MPB64 and IS6110 primers specific for M. tuberculosis for rapid diagnosis of GITB. MATERIALS AND
methodsMPCR was performed on colonoscopy biopsy specimens on 11 GITB confirmed (culture/AFB/histopathology was positive), 29 GITB suspected and 30 Non GITB (control group) patients.
resultsMPB64 PCR had sensitivity and specificity of 90% and 100% for confirmed GITB cases. In 29 clinically diagnosed but unconfirmed GITB cases, MPCR was positive in 72.41%. MPCR was negative in all control group patients. The overall sensitivity and specificity of microscopy, culture, histopathology and MPCR was 5%, 2% 20% and 77.5% and 100%, 100%, 100% and 100% respectively.
conclusionMPCR has good sensitivity and specificity in diagnosing gastrointestinal tuberculosis.
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