Evidence map›Paper›PMID 23853102›Full record

ArticleChemistry (Weinheim an der Bergstrasse, Germany)2013

More than meets the eye: conformational switching of a stacked dialkoxynaphthalene-naphthalenetetracarboxylic diimide (DAN-NDI) foldamer to an NDI-NDI fibril aggregate.

Cameron Peebles, Rebecca Piland, Brent L Iverson

Abstract read
In one paragraph

Article in Chemistry (Weinheim an der Bergstrasse, Germany), 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Cameron PeeblesDepartment of Chemistry & Biochemistry, The University of Austin at Texas, Welch Hall 2.204, 105 E. 24th Str. STOP A5300, Austin, TX 78712, USA.
Rebecca Piland
Brent L Iverson

Funding

Exploring Aromatic Donor-Acceptor Interactions in WaterR01GM069647 · NIGMS · UNIVERSITY OF TEXAS AUSTIN · PI IVERSON, BRENT L · 2005 to 2008
$987k
NIGMS NIH HHS GM-069647NIGMS NIH HHS R01 GM069647
6 · The paper itself

Abstract

The thermally induced conformational switching of a stacked dialkxoynaphthalene-naphthalenetetracarboxylic diimide (DAN-NDI) amphiphilic foldamer to an NDI-NDI fibril aggregate is described. The aggregated fibril structures were explored by UV/Vis, circular dichroism (CD), atomic-force microscopy (AFM), and TEM techniques. Our findings indicate that the aromatic DAN-NDI interactions of the original foldamer undergoes transformation to a fibrillar assembly with aromatic NDI-NDI stacked interactions. These structural insights could help inform new molecular designs and increase our understanding of fibrillar assembly and aggregation process in aqueous solution.

Indexed as

ImidesMolecular ConformationNaphthalenesImidesNaphthalenesaggregationpi interactionsself-assemblysupramolecular chemistrysynthetic biology

Identifiers

PMID23853102
PMCPMC3825095

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.