ArticleForensic science, medicine, and pathology2013
Witnessed sleep-related seizure and sudden unexpected death in infancy: a case report.
Article in Forensic science, medicine, and pathology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed, 18 citations in OpenAlex.
- Sudden unexpected infant death, sudden unexplained death in childhood, and sudden unexpected death in epilepsy.Developmental medicine and child neurology · 2025Review
- Metabolic acidosis and sudden infant death syndrome: overlooked data provides insight into SIDS pathogenesis.World journal of pediatrics : WJP · 2025Review
- Sudden unexpected death in epilepsy: Respiratory mechanisms.Handbook of clinical neurology · 2022Review
- Seizure-related deaths in children: The expanding spectrum.Epilepsia · 2021Article
- Genetic Factors Underlying Sudden Infant Death Syndrome.The application of clinical genetics · 2021Review
- A de novo BRPF1 variant in a case of Sudden Unexplained Death in Childhood.European journal of medical genetics · 2020Article
- Impaired COTrends in neurosciences · 2019Review
- From unwitnessed fatality to witnessed rescue: Pharmacologic intervention in sudden unexpected death in epilepsy.Epilepsia · 2016Review
- Dentate gyrus abnormalities in sudden unexplained death in infants: morphological marker of underlying brain vulnerability.Acta neuropathologica · 2015Article
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
Abstract
Witnessed reports of sudden death are rare, but critical to deciphering its mechanism(s). We report such a death in a seemingly healthy 8-month-old boy in whom seizures and respiratory distress in the prone position were witnessed upon discovery during a sleep period. Following cardiopulmonary resuscitation, anoxic encephalopathy resulted in "brain death" and withdrawal of life support after 2 days. The autopsy did not reveal a primary anatomic cause of death. Metabolic evaluation failed to uncover an inborn error of ammonia, amino, organic, or fatty acid metabolism. Seizures in this case may have been secondary to cerebral hypoxia-ischemia complicating cardiorespiratory arrest of unknown etiology. Yet, they may represent the first manifestation of idiopathic epilepsy, triggering cardiopulmonary arrest, analogous to the terminal events postulated in sudden and unexplained death in epilepsy. This report alerts the forensic community to the possibility that sudden and unexplained death in infants may be due to seizures.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.