ArticleChild's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery2014
Clinical outcome of pediatric choroid plexus tumors: retrospective analysis from a single institute.
Article in Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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15 citing papers in PubMed, 48 citations in OpenAlex.
- CPT-SIOP registry: evaluation of risk factors for disease progression in pediatric choroid plexus papilloma.Journal of neuro-oncology · 2025Article
- Predictive factors in the management of hydrocephalus and cerebrospinal fluid-related complications in pediatric choroid plexus tumors: a single-center experience.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2025Article
- Application of Endoscopic Underwater Surgery for Brain Tumors from Ventricle to Cistern: A Report of Pediatric and Elderly Cases.NMC case report journal · 2025Article
- Posterior fossa choroidplexus papilloma in the pediatric population: case series and literature review.Arquivos de neuro-psiquiatria · 2023Review
- Cystic dissemination of choroid plexus papilloma: illustrative cases.Journal of neurosurgery. Case lessons · 2022Article
- Final results of the Choroid Plexus Tumor study CPT-SIOP-2000.Journal of neuro-oncology · 2022Article
- Case Report: Reversible Hyperglycemia Following Rapamycin Treatment for Atypical Choroid Plexus Papilloma in an Infant.Frontiers in endocrinology · 2022Article
- Management of choroid plexus tumors-an institutional experience.Acta neurochirurgica · 2019Article
- Choroid plexus tumours on MRI: similarities and distinctions in different grades.Cancer imaging : the official publication of the International Cancer Imaging Society · 2019Article
- Review
- A French retrospective study on clinical outcome in 102 choroid plexus tumors in children.Journal of neuro-oncology · 2017Article
- Increased NG2 and SOX2 expression is associated with high-grade choroid plexus tumors.Oncology letters · 2017Article
- The role of chemotherapy and surgical removal in the treatment of Choroid Plexus carcinomas and atypical papillomas.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2015Article
- Pediatric choroid plexus tumors: epidemiology, treatments, and outcome analysis on 202 children from the SEER database.Journal of neuro-oncology · 2015Article
- Role of available adjuvant therapies following surgical resection of atypical choroid plexus papilloma-a systematic review and pooled analysis.Neuro-oncology advancesArticle
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Authors and funding
10 authors at 5 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundChoroid plexus tumor is a rare brain tumor with variable clinical features according to the histological grade. We reviewed the treatment outcome of 23 children, focusing on the biological behavior of the atypical choroid plexus papilloma (ACPP) and the current therapeutic strategy in choroid plexus carcinoma (CPC).
methodsThe demographics, clinical features, surgical treatments, adjuvant therapies, and survival were reviewed.
resultsThe median age at diagnosis was 18 months--55 months for choroid plexus papilloma (CPP), 8 months for ACPP, and 15 months for CPC. Gross total resections were achieved in seven of eight patients with CPP, seven of seven with ACPP, and three of eight with CPC. Seven patients with CPC received chemotherapy. Four patients received high-dose chemotherapy (HDCT) and autologous peripheral blood stem cell transplantation (aPBSCT), and three among them have survived. Four patients with CPC received radiotherapy. One CPP patient and one CPC patient underwent radiosurgery. All CPP and ACPP patients have survived. The overall survival rate of the CPC patients was 62.5% in the first year and 42.9% in the second year. The progression-free survival rate of the CPC patients was 50% in the first year and 0% in the second year. Seven patients underwent permanent cerebrospinal fluid diversion surgery because of hydrocephalus or subdural effusion.
conclusionCPP and ACPP were surgically curable. Multi-modal treatments are necessary in the management of CPC with poor prognosis. HDCT and aPBSCT may be important to treat infants for whom radiotherapy is limited. Hydrocephalus and subdural effusion should be resolved with appropriate management.
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