ArticleSleep & breathing = Schlaf & Atmung2014
Acute sleep deprivation is associated with increased arterial stiffness in healthy young adults.
Article in Sleep & breathing = Schlaf & Atmung, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 48 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
48 citing papers in PubMed, 1 synthesis or guideline pooled it, 81 citations in OpenAlex.
- Association of Subjective and Objective Sleep Duration as well as Sleep Quality with Non-Invasive Markers of Sub-Clinical Cardiovascular Disease (CVD): A Systematic Review.Journal of atherosclerosis and thrombosis · 2017Pooled it
- Sleep duration and risk of stroke mortality among Chinese adults: Singapore Chinese health study.Stroke · 2014Trial
- The Influence of Optimal Sleep Onset Time and Duration on Risk of Stroke: A Community-Based, Cross-Sectional Study.Journal of clinical medicine · 2025Article
- Arterial stiffness and vascular aging: mechanisms, prevention, and therapy.Signal transduction and targeted therapy · 2025Review
- Influence of sleep and cardiovascular health on cognitive trajectories in older adults.Neurobiology of aging · 2025Observational
- Associations of sleep pattern, sleep duration, bedtime, rising time and cardiovascular disease: Data from NHANES (2017-2020).PloS one · 2025Article
- Effects of a 1-hour per night week-long sleep extension in college students on cardiometabolic parameters, hydration status, and physical activity: A pilot study.Sleep health · 2024Article
- Linear Relationship between Hepatic Steatosis Index and Major Adverse Cardiovascular Events in Hypertensive Patients with Obstructive Sleep Apnea: A Real-World Cohort Study from China.Reviews in cardiovascular medicine · 2023Article
- Vascular function in hypertension: does gender dimension matter?Journal of human hypertension · 2023Review
- Short sleep duration associated with the incidence of cardio-cerebral vascular disease: a prospective cohort study in Shanghai, China.BMC cardiovascular disorders · 2023Article
- Cardiovascular measures display robust phenotypic stability across long-duration intervals involving repeated sleep deprivation and recovery.Frontiers in neuroscience · 2023Article
- The Oscillometric Pulse Wave Analysis Is Useful in Evaluating the Arterial Stiffness of Obese Children with Relevant Cardiometabolic Risks.Journal of clinical medicine · 2022Article
- Sleep loss effects on physiological and cognitive responses to systemic environmental hypoxia.Frontiers in physiology · 2022Review
- Effects of 24-h acute total sleep deprivation on physiological coupling in healthy young adults.Frontiers in neuroscience · 2022Article
- Sleep and cardiovascular outcomes in relation to nocturnal hypertension: the J-HOP Nocturnal Blood Pressure Study.Hypertension research : official journal of the Japanese Society of Hypertension · 2021Article
- Acute Myocardial Infarction and Daylight Saving Time Transitions: Is There a Risk?Clocks & sleep · 2021Article
- Post-Exertional Malaise May Be Related to Central Blood Pressure, Sympathetic Activity and Mental Fatigue in Chronic Fatigue Syndrome Patients.Journal of clinical medicine · 2021Article
- Left Ventricular Ejection Time Measured by Echocardiography Differentiates Neurobehavioral Resilience and Vulnerability to Sleep Loss and Stress.Frontiers in physiology · 2021Article
- A Primer on Repeated Sitting Exposure and the Cardiovascular System: Considerations for Study Design, Analysis, Interpretation, and Translation.Frontiers in cardiovascular medicine · 2021Review
- Long sleep duration and risk of increased arterial stiffness in a Chinese population.Medicine · 2020Observational
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundArterial stiffness and its hemodynamic consequences are known to be associated with increased cardiovascular morbidity and mortality. Pulse wave velocity (PWV) and augmentation index (AIx) are noninvasive indicators of the arterial stiffness and wave reflection. Sleep deprivation (SD) is known to be associated with increased incidence of adverse cardiovascular events. The aim of this study was to investigate whether there is an association between acute SD and arterial stiffness parameters in healthy adults, which has not been studied previously.
methodsThe study population consisted of 42 healthy volunteers (18 males, mean age 30.0 ± 4.5 years). Measurements of arterial stiffness were carried out by using a Mobil-O-Graph arteriograph system. Arterial stiffness measurements were obtained both after a night with regular sleep (RS) and after a night with SD.
resultsMean sleep time was significantly lower after the night of SD when compared after RS (0.73 ± 1.39 versus 7.33 ± 0.52 h, p<0.001). Peripheral systolic blood pressure, peripheral pulse pressure, and cardiac output were significantly higher after SD when compared after RS (p=0.032, 0.007, and 0.003, respectively). PWV was significantly higher (5.33 ± 0.46 versus 5.15 ± 0.26 m/s, p=0.001), and AIx was significantly lower (20.5 ± 11.9 versus 26.0 ± 8.4 %, p=0.008) after the night of SD when compared after the RS. While PWV was significantly higher (p=0.008), and AIx was significantly lower (p=0.039) in male subjects, only PWV was significantly higher (p=0.009) in female subjects. Sleep time correlated with AIx (p=0.034; r=0.233) and inversely correlated with PWV (p=0.044; r=-0.222).
conclusionIn the present study, we demonstrated that even one night of SD is associated with increased arterial stiffness in healthy adults. The present findings suggest that adverse effects of SD on cardiovascular system might be at least in part due to increased arterial stiffness which needs to be tested with large-scale studies and in the chronic SD setting.
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