ArticleNeuroradiology2013
Intravoxel incoherent motion diffusion-weighted MR imaging of gliomas: feasibility of the method and initial results.
Article in Neuroradiology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 55 papers, 3 of them syntheses that pooled it.
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Who cites it
55 citing papers in PubMed, 3 syntheses or guidelines pooled it, 101 citations in OpenAlex.
- Congress of neurological surgeons systematic review and evidence-based guidelines for the role of imaging in newly diagnosed WHO grade II diffuse glioma in adults: update.Journal of neuro-oncology · 2025Pooled it
- An evidence-based approach to assess the accuracy of intravoxel incoherent motion imaging for the grading of brain tumors.Medicine · 2018Pooled it
- Optimal differentiation of high- and low-grade glioma and metastasis: a meta-analysis of perfusion, diffusion, and spectroscopy metrics.Neuroradiology · 2016Pooled it
- Combination of IVIM-DWI and 3D-ASL for differentiating true progression from pseudoprogression of Glioblastoma multiforme after concurrent chemoradiotherapy: study protocol of a prospective diagnostic trial.BMC medical imaging · 2017Trial
- Towards Clinical Translation of Intravoxel Incoherent Motion MRI: Acquisition and Analysis Consensus Recommendations.Journal of magnetic resonance imaging : JMRI · 2026Article
- Study on the application value of histogram parameters from reduced field-of-view VOI in rectal cancer.Abdominal radiology (New York) · 2026Article
- Assessment of Intravoxel Incoherent Motion Diffusion-Weighted Imaging in Insomnia.Brain and behavior · 2025Article
- Multi‑parameter quantitative magnetic resonance imaging in the early assessment of radiation‑induced parotid damage in patients with nasopharyngeal carcinoma following intensity‑modulated radiotherapy.Oncology letters · 2024Article
- Intravoxel incoherent motion for differentiating residual/recurrent tumor from post-treatment change in patients with high-grade glioma.The neuroradiology journal · 2023Article
- A three-component multi-b-value diffusion-weighted imaging might be a useful biomarker for detecting microstructural features in gliomas with differences in malignancy and IDH-1 mutation status.European radiology · 2023Article
- Simultaneous Quantification of Anisotropic Microcirculation and Microstructure in Peripheral Nerve.Journal of clinical medicine · 2022Article
- Feasibility of intravoxel incoherent motion in the assessment of tumor microvasculature and blood-brain barrier integrity: a case-based evaluation of gliomas.Magma (New York, N.Y.) · 2022Article
- Intravoxel Incoherent Motion Magnetic Resonance Imaging Used in Preoperative Screening of High-Risk Patients With Moyamoya Disease Who May Develop Postoperative Cerebral Hyperperfusion Syndrome.Frontiers in neuroscience · 2022Article
- Intravoxel Incoherent Motion Diffusion-Weighted Imaging and 3D-ASL to Assess the Value of Ki-67 Labeling Index and Grade in Glioma.Scanning · 2022Article
- Non-Invasive Evaluation of Cerebral Hemodynamic Changes After Surgery in Adult Patients With Moyamoya Using 2D Phase-Contrast and Intravoxel Incoherent Motion MRI.Frontiers in surgery · 2022Article
- Intravoxel incoherent motion (IVIM) modeling of diffusion MRI during chemoradiation predicts therapeutic response in IDH wildtype glioblastoma.Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology · 2021Article
- Monoexponential, biexponential and stretched exponential models of diffusion weighted magnetic resonance imaging in glioma in relation to histopathologic grade and Ki-67 labeling index using high B values.American journal of translational research · 2021Article
- A Fast Protocol for Multiparametric Characterisation of Diffusion in the Brain and Brain Tumours.Frontiers in oncology · 2021Article
- Statistical Evaluation of Different Mathematical Models for Diffusion Weighted Imaging of Prostate Cancer Xenografts in Mice.Frontiers in oncology · 2021Article
- The diagnostic function of intravoxel incoherent motion for distinguishing between pilocytic astrocytoma and ependymoma.PloS one · 2021Article
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionThe purpose of this study was to evaluate the feasibility of intravoxel incoherent motion (IVIM) imaging and its value in differentiating the histologic grade among human gliomas.
methodsThe IVIM model generated parametric images for apparent diffusion coefficient ADC, slow diffusion coefficient D (or D slow), fast diffusion coefficient D* (or D fast), and fractional perfusion-related volume f in 22 patients with gliomas (WHO grade II-IV) using monopolar Stejskal-Tanner diffusion-weighted imaging (DWI) scheme and 14 b values ranging from 0 s/mm2 to a maximum of 1,300 s/mm2. A region-of-interest analysis on the tumor as well as in the white matter was conducted. The parameter values were tested for significant differences. The repeatability of the measurements was tested by coefficient of variation and Bland-Altman plots.
resultsD, D*, and f in the high-grade gliomas demonstrated significant differences compared to the healthy white matter. D* and f showed a significant difference between low- and high-grade gliomas. D tended to be slightly lower in the WHO grade II compared to WHO grade III-IV tumors. f and D* demonstrated higher coefficients of variation than the ADC and D in tumor. The Bland-Altman plots demonstrated satisfactory results without any outliers outside the mean ± 1.96 standard deviation.
conclusionThe IVIM-fitted post-processing of DWI-signal decay in human gliomas could show significantly different values of fractional perfusion-related volume and fast diffusion coefficient between low- and high-grade tumors, which might enable a noninvasive WHO grading in vivo.
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