SynthesisSupportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer2013
Cancer-related fatigue in the elderly.
Synthesis in Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
25 citing papers in PubMed, 2 syntheses or guidelines pooled it, 57 citations in OpenAlex.
- Prevalence and risk factors for cancer-related fatigue in women with malignant gynecological tumors: a meta-analysis and systematic review.BMC cancer · 2025Pooled it
- Prevalence and Impact of Fatigue on Quality of Life (QOL) of Cancer Patients Undergoing Chemotherapy: A Systematic Review and Meta-Analysis.Asian Pacific journal of cancer prevention : APJCP · 2023Pooled it
- Melatonin supplementation for quality of life in older patients with advanced cancer: a randomized controlled trial.BMC geriatrics · 2025Trial
- Project HERO: a randomized trial of Tai Chi qigong versus intensity-matched exercise and usual care for fatigue in older male cancer survivors.BMC complementary medicine and therapies · 2025Trial
- The effect of YOCAS©® yoga on cancer-related fatigue and quality of life in older (60+) vs. younger (≤ 59) cancer survivors: Secondary analysis of a nationwide, multicenter, phase 3 randomized controlled trial.Journal of geriatric oncology · 2024Trial
- Risk stratification using a nomogram model for postoperative cancer-related fatigue in elderly survivors following early-stage non-small cell lung cancer resection.BMC pulmonary medicine · 2025Article
- The definitions, assessment, and dimensions of cancer-related fatigue: A scoping review.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2024Article
- Cardiovascular Concerns, Cancer Treatment, and Biological and Chronological Aging in Cancer:JACC. CardioOncology · 2024Review
- Implementing fencing as adapted physical activity in non-metastatic breast cancer patients: design and early rehabilitation strategy of the FENICE study protocol.Frontiers in oncology · 2024Article
- Perceived Injustice in Cancer Survivors: Population-Specific Cut-Off Score and Relations with Personal Factors, Symptoms and Quality of Life-A Cross-Sectional Study.Journal of clinical medicine · 2023Article
- Improved Survival and Quality of Life Through an Integrative, Multidisciplinary Oncological Approach: Pathophysiological Analysis of Four Clinical Cancer Cases and Review of the Literature.Frontiers in pharmacology · 2022Article
- Article
- An Exploratory Analysis of the Association Between Catechol-O-Methyltransferase and Response to a Randomized Open-Label Placebo Treatment for Cancer-Related Fatigue.Frontiers in psychiatry · 2021Article
- Social Relationships and Functional Impairment in Aging Cancer Survivors: A Longitudinal Social Network Study.The Gerontologist · 2020Article
- Prospective comparison of the value of CRASH and CARG toxicity scores in predicting chemotherapy toxicity in geriatric oncology.Oncology letters · 2019Article
- Change in Quality of Life after a Cancer Diagnosis among a Nationally Representative Cohort of Older Adults in the US.Cancer investigation · 2019Article
- Fatigue in the general population: German normative values of the EORTC QLQ-FA12.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2018Article
- Evaluation of the effects of a clinically implemented exercise program on physical fitness, fatigue, and depression in cancer survivors.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2018Article
- Intermittent androgen deprivation therapy: recommendations to improve the management of patients with prostate cancer following the GRADE approach.Cancer management and research · 2018Article
- In situ macrophage phenotypic transition is affected by altered cellular composition prior to acute sterile muscle injury.The Journal of physiology · 2017Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeCancer is a disease of the elderly: 60 % of tumours occur in patients aged 65 years or older. Cancer-related fatigue is a common symptom experienced by cancer patients and cancer survivors that profoundly affects all aspects of the quality of life. Although it has been estimated that up to 70 % of elderly with cancer experience fatigue, this symptom is still largely ignored in ageing population.
methodsWe performed a systematic review of the literature identified by MEDLINE.
resultsThe relationship between ageing process and pathogenesis of cancer-related fatigue is still not fully understood.
conclusionsAgeing is associated with an increased prevalence of chronic diseases, decreased functional reserve in multiple organ systems and enhanced susceptibility to stress. Ageing and the concomitant presence of a condition of frailty may predispose to the presence of fatigue. Nevertheless, only few studies have to date specifically assessed the impact of fatigue in the geriatric population. Since cancer-related fatigue is a peculiarly debilitating condition characteristic of elderly cancer patient population, we suggest the early recognition and thorough evaluation of the symptom fatigue, its co-existing causes (i.e. anaemia, mood disorders and sleep disturbances) and co-morbidities (i.e., endocrine disorders, metabolic, cardiovascular and liver diseases).
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.