Evidence map›Paper›PMID 23851317›Full record

ReviewGut microbes

Biomarkers of Helicobacter pylori-associated gastric cancer.

Cara L Cooke, Javier Torres, Jay V Solnick

Open access · bronzeAbstract readReview
In one paragraph

Review in Gut microbes. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
2.9field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 25 citations in OpenAlex.

  1. Comparative insights intoFrontiers in microbiology · 2025
    Review
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Evaluation of altered expression ofJournal of gastrointestinal oncology · 2018
    Article
  8. Review
  9. Host pathogen interactions inWorld journal of gastroenterology · 2017
    Review
  10. Article
  11. Dietary amelioration of Helicobacter infection.Nutrition research (New York, N.Y.) · 2015
    Review
  12. Implementation of gastric cancer screening - the global experience.Best practice & research. Clinical gastroenterology · 2014
    Review
  13. Intestinal microbiome and digoxin inactivation: meal plan for digoxin users?World journal of microbiology & biotechnology · 2014
    Review
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

Cara L CookeDepartments of Medicine and Microbiology & Immunology; University of California; Davis School of Medicine; Davis, CA USA; Center for Comparative Medicine; University of California; Davis School of Medicine; Davis, CA USA.
Javier TorresInfectious Diseases Research Unit; Instituto Mexicano del Seguro Social; Mexico City, Mexico.
Jay V SolnickDepartments of Medicine and Microbiology & Immunology; University of California; Davis School of Medicine; Davis, CA USA; Center for Comparative Medicine; University of California; Davis School of Medicine; Davis, CA USA; California National Primate Research Center; University of California; Davis School of Medicine; Davis, CA USA.
University of California System · USMexican Social Security Institute · MX

Funding

Serum biomarkers for early detection of H. pylori-associated gastric cancerR01CA136647 · NCI · UNIVERSITY OF CALIFORNIA AT DAVIS · PI SOLNICK, JAY V. · 2009 to 2013
$1.5M
NCI NIH HHS CA R01136647
6 · The paper itself

Abstract

Helicobacter pylori-associated gastric cancer is a major cause of morbidity and mortality worldwide, and is predicted to become even more common in developing countries as the population ages. Since gastric cancer develops slowly over years to decades, and typically progresses though a series of well-defined histologic stages, cancer biomarkers have potential to identify asymptomatic individuals in whom surgery might be curative, or even those for whom antibiotics to eradicate H. pylori could prevent neoplastic transformation. Here we describe some of the challenges of biomarker discovery, summarize current approaches to biomarkers of gastric cancer, and explore some recent novel strategies.

Indexed as

Helicobacter pyloriBiomarkersHelicobacter InfectionsHumansRisk FactorsStomach NeoplasmsBiomarkersbiomarkersgastric cancerhelicobacter pylori

Identifiers

PMID23851317
PMCPMC3928163
OpenAlexW2051750467

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.