Evidence map›Paper›PMID 23851303›Full record

ArticleOptometry and vision science : official publication of the American Academy of Optometry2013

Responsiveness of the EQ-5D to the effects of low vision rehabilitation.

Alexis G Malkin, Judith E Goldstein, Monica S Perlmutter, Robert W Massof, Low Vision Research Network Study Group

Abstract read
In one paragraph

Article in Optometry and vision science : official publication of the American Academy of Optometry, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Measurement properties of the EQ-5D in populations with a mean age of ≥ 75 years: a systematic review.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2023
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  12. Predictors of vision-related quality of life in patients with macular oedema receiving intra-vitreal anti-VEGF treatment.Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists) · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Alexis G MalkinLions Vision Research and Rehabilitation Center, Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, Maryland 21287, USA. amalkin2@jhmi.edu
Judith E Goldstein
Monica S Perlmutter
Robert W Massof
Low Vision Research Network Study Group

Funding

VISION DISABILITIES IN LOW VISIONR01EY012045 · NEI · JOHNS HOPKINS UNIVERSITY · PI MASSOF, ROBERT W. · 1999 to 2007
$3.8M
Low Vision Devices and Rehabilitation ServicesR34EY018696 · NEI · JOHNS HOPKINS UNIVERSITY · PI MASSOF, ROBERT W. · 2008 to 2009
$500k
NEI NIH HHS EY012045NEI NIH HHS EY018696NEI NIH HHS R01 EY012045NEI NIH HHS R34 EY018696
6 · The paper itself

Abstract

purposeThis study is an evaluation of the responsiveness of preference-based outcome measures to the effects of low vision rehabilitation (LVR). It assesses LVR-related changes in EQ-5D utilities in patients who exhibit changes in Activity Inventory (AI) measures of visual ability.

methodsTelephone interviews were conducted on 77 low-vision patients out of a total of 764 patients in the parent study of "usual care" in LVR. Activity Inventory results were filtered for each patient to include only goals and tasks that would be targeted by LVR.

resultsThe EQ-5D utilities have weak correlations with all AI measures but correlate best with AI goal scores at baseline (r = 0.48). Baseline goal scores are approximately normally distributed for the AI, but EQ-5D utilities at baseline are skewed toward the ceiling (median, 0.77). Effect size for EQ-5D utility change scores from pre- to post-LVR was not significantly different from zero. The AI visual function ability change scores corresponded to a moderate effect size for all functional domains and a large effect size for visual ability measures estimated from AI goal ratings.

conclusionsThis study found that the EQ-5D is unresponsive as an outcome measure for LVR and has poor sensitivity for discriminating low vision patients with different levels of ability.

Indexed as

Sickness Impact ProfileSurveys and QuestionnairesActivities of Daily LivingAdultAgedAged, 80 and overFemaleHumansMaleMiddle AgedOutcome Assessment, Health CareQuality of LifeVision, LowYoung Adult

Identifiers

PMID23851303
PMCPMC6730640

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.