Evidence map›Paper›PMID 23851181›Full record

Observational studyThe Journal of urology2014

Treatment status and progression or regression of lower urinary tract symptoms in a general adult population sample.

Nancy N Maserejian, Shan Chen, Gretchen R Chiu, Andre B Araujo, Varant Kupelian, Susan A Hall, John B McKinlay

Abstract readObservational Study
In one paragraph

Observational study in The Journal of urology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed, 1 pooled it
8.0field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 1 synthesis or guideline pooled it, 45 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Article
  6. Non-linear Relationship Between Body Mass Index and Lower Urinary Tract Symptoms in Korean Males.Journal of preventive medicine and public health = Yebang Uihakhoe chi · 2019
    Article
  7. Review
  8. Article
  9. Article
  10. Review
  11. Bladder Symptoms in the Early Menopausal Transition.Journal of women's health (2002) · 2016
    Article
  12. The Epidemiology of Pelvic Floor Disorders and Childbirth: An Update.Obstetrics and gynecology clinics of North America · 2016
    Review
  13. Review
  14. Review
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Nancy N MaserejianNew England Research Institutes, Watertown, Massachusetts. Electronic address: nmaserejian@neriscience.com.
Shan ChenNew England Research Institutes, Watertown, Massachusetts.
Gretchen R ChiuNew England Research Institutes, Watertown, Massachusetts.
Andre B AraujoNew England Research Institutes, Watertown, Massachusetts.
Varant KupelianNew England Research Institutes, Watertown, Massachusetts.
Susan A HallNew England Research Institutes, Watertown, Massachusetts.
John B McKinlayNew England Research Institutes, Watertown, Massachusetts.
New England Research Institutes · US

Funding

Trajectories of Urologic Disease: Follow-up of BACHU01DK056842 · NIDDK · NEW ENGLAND RESEARCH INSTITUTES, INC. · PI MCKINLAY, JOHN B · 2001 to 2011
$15.7M
NIDDK NIH HHS U01 DK056842NIDDK NIH HHS U01DK56842
6 · The paper itself

Abstract

purposeWe report progression and regression of lower urinary tract symptoms in a population based cohort by race/ethnicity, gender, age and lower urinary tract symptom medication use. MATERIALS AND

methodsThe BACH (Boston Area Community Health) Survey enrolled 5,502 participants 30 to 79 years old of black, Hispanic or white race/ethnicity. The 5-year followup interviews were completed by 1,610 men and 2,534 women for a conditional response rate of 80%. Population weighted estimates of lower urinary tract symptoms severity were assessed using the AUASI (American Urological Association symptom index) and analyzed using multivariate models.

resultsSymptom progression (increase in AUASI score of 3 or more points) was reported by 21% to 33% of participants and regression (decrease 3 or greater) by 30% to 44% of participants, most commonly women and Hispanic participants. Age and higher body mass index were associated with progression (p <0.01), but not with regression. Lower urinary tract symptom medication use at baseline only was associated with improved symptoms scores 5 years later (multivariate adjusted OR 3.10, 95% CI 1.28-7.51, compared to nonusers), whereas using medication at baseline and followup was associated with similar rates of progression and regression as observed among participants not using lower urinary tract symptom medication at either point.

conclusionsLower urinary tract symptoms persisted at followup for approximately half of the population experiencing symptoms at baseline, including many men and women using lower urinary tract symptom medications. However, overall lower urinary tract symptom medication use and surgical treatment appeared beneficial for symptom control at 5-year followup. Age and body mass index were associated with symptom worsening, and Hispanic ethnicity was associated with greater symptom fluctuation. Clinicians should consider the higher likelihood of lower urinary tract symptom progression for older or heavier patients, and monitor responsiveness to lower urinary tract symptom medication.

Indexed as

AdultAgedBostonCohort StudiesDisease ProgressionFemaleHealth SurveysHumansLower Urinary Tract SymptomsMaleMiddle AgedBMIbody mass indexepidemiologylower urinary tract symptomsLUTSoveractiveprostatic hyperplasiaurinary bladderurination disorders

Identifiers

PMID23851181
PMCPMC4012380
OpenAlexW2036306441

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.