ArticleApplied and environmental microbiology2013
Interaction of Lactobacillus fermentum BGHI14 with rat colonic mucosa: implications for colitis induction.
Article in Applied and environmental microbiology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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Who cites it
22 citing papers in PubMed.
- Therapeutic Effect ofMicroorganisms · 2024Article
- Postbiotic lactobacilli induce cutaneous antimicrobial response and restore the barrier to inhibit the intracellular invasion of Staphylococcus aureus in vitro and ex vivo.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2024Article
- Effect of Electroacupuncture at Zusanli (ST36) on Intestinal Microbiota in Rats With Chronic Atrophic Gastritis.Frontiers in genetics · 2022Article
- Probiotic-mediated p38 MAPK immune signaling prolongs the survival of Caenorhabditis elegans exposed to pathogenic bacteria.Scientific reports · 2021Article
- Yogurt Produced by Novel Natural Starter Cultures Improves Gut Epithelial Barrier In Vitro.Microorganisms · 2020Article
- Gut Microbiota Dysbiosis Associated With Altered Production of Short Chain Fatty Acids in Children With Neurodevelopmental Disorders.Frontiers in cellular and infection microbiology · 2020Article
- Antioxidant and Antiproliferative Activity ofFrontiers in microbiology · 2020Article
- Oral neonatal antibiotic treatment perturbs gut microbiota and aggravates central nervous system autoimmunity in Dark Agouti rats.Scientific reports · 2019Article
- The Influence of Heat-KilledFrontiers in microbiology · 2019Article
- GABA-Producing Natural Dairy Isolate From Artisanal Zlatar Cheese Attenuates Gut Inflammation and Strengthens Gut Epithelial BarrierFrontiers in microbiology · 2019Article
- The Role of Macrophage Migration Inhibitory Factor in the Function of Intestinal Barrier.Scientific reports · 2018Article
- Gut Microbiota Confers Resistance of Albino Oxford Rats to the Induction of Experimental Autoimmune Encephalomyelitis.Frontiers in immunology · 2018Article
- Exopolysaccharide Produced by Probiotic StrainFrontiers in pharmacology · 2018Article
- Probiotics or pro-healers: the role of beneficial bacteria in tissue repair.Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society · 2017Review
- In vitro and in vivo antagonistic activity of new probiotic culture against Clostridium difficile and Clostridium perfringens.BMC microbiology · 2017Article
- Promotion of Early Gut Colonization by Probiotic Intervention on Microbiota Diversity in Pregnant Sows.Frontiers in microbiology · 2017Article
- Article
- Bacterial overgrowth and diversification of microbiota in gastric cancer.European journal of gastroenterology & hepatology · 2016Article
- Correlation of Gut Microbiota Composition with Resistance to Experimental Autoimmune Encephalomyelitis in Rats.Frontiers in microbiology · 2016Article
- EPS-SJ Exopolisaccharide Produced by the Strain Lactobacillus paracasei subsp. paracasei BGSJ2-8 Is Involved in Adhesion to Epithelial Intestinal Cells and Decrease on E. coli Association to Caco-2 Cells.Frontiers in microbiology · 2016Article
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The present study was carried out to test the colonic mucosal response of rats to oral supplementation with Lactobacillus fermentum BGHI14 and to correlate the tissue reaction to trinitrobenzenesulfonate (TNBS)-induced colitis with mucosal barrier alterations caused by bacterial ingestion. An immune cell-mediated reaction of healthy colonic tissue was noticed after bacterial feeding. After prolonged bacterial treatment, the observed reaction had retreated to normality, but the mRNA levels of proinflammatory cytokines interleukin-1β (IL-1β) and tumor necrosis factor alpha (TNF-α) remained elevated. These data point to the chronic low-grade inflammation that could be caused by long-term probiotic consumption. Although no detrimental effects of bacterial pretreatment were noticed in colitic rats, at least in the acute state of disease, the results obtained in our study point to the necessity of reassessment of existing data on the safety of probiotic preparations. Additionally, probiotic effects in experimental colitis models might depend on time coordination of disease induction with treatment duration.
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