ArticlePsychoneuroendocrinology2013
Autonomic regulation across phases of the menstrual cycle and sleep stages in women with premenstrual syndrome and healthy controls.
Article in Psychoneuroendocrinology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
41 citing papers in PubMed, 1 synthesis or guideline pooled it, 76 citations in OpenAlex.
- Heart rate variability and overtraining in soccer players: A systematic review.Physiological reports · 2025Pooled it
- Pre-sleep milk-derived proteins do not impair sleep or recovery in elite female athletes.Journal of the International Society of Sports Nutrition · 2026Trial
- Effects of sleep fragmentation and partial sleep restriction on heart rate variability during night.Scientific reports · 2023Trial
- Using insertable cardiac monitors to test determinants of heart rate and activity in captive baboons.Animal biotelemetry · 2026Article
- Wearable-measured heart rate variability and premenstrual disorder symptoms across menstrual cycle.Archives of women's mental health · 2026Article
- Exploratory Correlation Analysis of Respiratory Waveform, Instantaneous Respiratory Depth and Rate in Relation to Parasympathetic Indices During Spontaneous Breathing.Bioengineering (Basel, Switzerland) · 2026Article
- Decoding menstrual health across the lifespan: a scoping review of digital health tools in research.medRxiv : the preprint server for health sciences · 2026Article
- Decoding menstrual health across the lifespan: a scoping review of digital health tools in research.npj women's health · 2026Article
- Heart Rate Variability Applications in Medical Specialties: A Narrative Review.Applied psychophysiology and biofeedback · 2025Review
- Sex Differences in the Association between Sleep Quality and Excess Weight: Exploring Lifestyle and Health-Related Mediators.Sleep science (Sao Paulo, Brazil) · 2025Article
- Slow nocturnal body cooling during sleep increases interbeat intervals and is tightly coupled to high-frequency heart rate variability in healthy men.Physiological reports · 2025Article
- A gender-integrated biopsychosocial model to understand cardiovascular risk in women working under environmental hazards: the case of chronic intermittent hypoxia.Frontiers in public health · 2025Review
- A Novel method for quantifying fluctuations in wearable derived daily cardiovascular parameters across the menstrual cycle.NPJ digital medicine · 2024Article
- Effect of menstrual cycle and menopause on human gastric electrophysiology.American journal of physiology. Gastrointestinal and liver physiology · 2024Article
- Proof of mechanism investigation of Transcutaneous auricular vagus nerve stimulation through simultaneous measurement of autonomic functions: a randomized controlled trial protocol.BioPsychoSocial medicine · 2024Article
- Effect of pranayama on sympatho-vagal imbalance and cognitive deficit in premenstrual syndrome.Journal of family medicine and primary care · 2024Article
- Effects of menstrual cycle on hemodynamic and autonomic responses to central hypovolemia.Frontiers in cardiovascular medicine · 2024Article
- The behavioral and physiological correlates of affective mood switching in premenstrual dysphoric disorder.Frontiers in psychiatry · 2024Review
- Can Wrist-Worn Medical Devices Correctly Identify Ovulation?Sensors (Basel, Switzerland) · 2023Observational
- Sleep apnea syndrome associated with gonadal hormone imbalance (Review).Biomedical reports · 2023Review
Corrections and comments
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Authors and funding
5 authors at 3 institutions in 3 countries.
Funding
Abstract
To investigate the influence of menstrual cycle phase and the presence of severe premenstrual symptoms on cardiac autonomic control during sleep, we performed heart rate variability (HRV) analysis during stable non-rapid eye movement (NREM) and REM sleep in 12 women with severe premenstrual syndrome and 14 controls in the mid-follicular, mid-luteal, and late-luteal phases of the menstrual cycle. Heart rate was higher, along with lower high frequency (HF) power, reflecting reduced vagal activity, and a higher ratio of low frequency (LF) to high frequency power, reflecting a shift to sympathetic dominance, in REM sleep compared with NREM sleep in both groups of women. Both groups of women had higher heart rate during NREM and REM sleep in the luteal phase recordings compared with the mid-follicular phase. HF power in REM sleep was lowest in the mid-luteal phase, when progesterone was highest, in both groups of women. The mid-luteal phase reduction in HF power was also evident in NREM sleep in control women but not in women with PMS, suggesting some impact of premenstrual syndrome on autonomic responses to the hormone environment of the mid-luteal phase. In addition, mid-luteal phase progesterone levels correlated positively with HF power and negatively with LF/HF ratio in control women in NREM sleep and with the LF/HF ratio during REM sleep in both groups of women. Our findings suggest the involvement of female reproductive steroids in cardiac autonomic control during sleep in women with and without premenstrual syndrome.
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Registered trials
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