Evidence map›Paper›PMID 23849656›Full record

ArticleExtreme physiology & medicine2013

Minute ventilation and heart rate relationship for estimation of the ventilatory compensation point at high altitude: a pilot study.

Gabriele Valli, Mattia Internullo, Alessandro M Ferrazza, Paolo Onorati, Annalisa Cogo, Paolo Palange

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Article in Extreme physiology & medicine, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

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4citing papers in PubMed
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4 citing papers in PubMed.

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5 · Who and what money

Authors and funding

6 authors.

Gabriele ValliLung Function Unit, Department of Public Health and Infectious Diseases, University of Rome "La Sapienza", viale Università 37, Rome, 00185, Italy. gabvalli@yahoo.it.
Mattia Internullo
Alessandro M Ferrazza
Paolo Onorati
Annalisa Cogo
Paolo Palange

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe ventilatory compensation point (VCP) is an exercise threshold which has been used in the design of training programs in sports medicine and rehabilitation. We recently demonstrated that changes in the slope of the minute ventilation to heart rate relationship (ΔV˙E/ΔHR) can be utilized for estimation of the VCP during incremental exercise at sea level (SL). We hypothesized that in hypoxic conditions, such as high altitude (HA), VCP can be also reliably estimated by ΔV˙E/ΔHR.

methodsAt SL and on immediate ascent to HA (5,050 m), six healthy subjects (42 ± 14 SD years) performed a maximal incremental exercise test on a cycle ergometer; O2 uptake (V˙O2), CO2 output (V˙CO2), V˙E, and HR were measured breath-by-breath. The ΔV˙E/ΔHR method for VCP estimation was compared to the standard method using the ventilatory equivalent for CO2 (V˙E/V˙CO2) and end-tidal PCO2 (PETCO2). The ΔV˙E/ΔHR slope values below (S1) and above (S2) VCP were computed by linear regression analysis.

resultsA significant difference between S1 and S2 was observed, at SL and HA, for both the ΔV˙E/ΔHR and V˙E/V˙CO2 methods for VCP estimation. A good agreement between the two methods (ΔV˙E/ΔHR vs. V˙E/V˙CO2) was found for both environmental conditions; the mean difference ± 2 SD of V˙O2 at VCP (VCP-V˙O2) was -22 ± 112 ml/min at SL and 39 ± 81 ml/min at HA. The VCP-V˙O2 was significantly lower at HA compared to SL; in addition, S1 and S2 mean values were significantly higher at HA compared to SL.

conclusionAt HA, VCP may be reliably estimated by the ΔV˙E/ΔHR method.

Identifiers

PMID23849656
PMCPMC3710187

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