ArticlePsychoneuroendocrinology2013
Lower subjective social status exaggerates interleukin-6 responses to a laboratory stressor.
Article in Psychoneuroendocrinology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 51 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
51 citing papers in PubMed, 4 syntheses or guidelines pooled it, 95 citations in OpenAlex.
- Pooled it
- Meta-analysis of Cerebrospinal Fluid Cytokine and Tryptophan Catabolite Alterations in Psychiatric Patients: Comparisons Between Schizophrenia, Bipolar Disorder, and Depression.Schizophrenia bulletin · 2018Pooled it
- The effects of acute psychological stress on circulating and stimulated inflammatory markers: A systematic review and meta-analysis.Brain, behavior, and immunity · 2017Pooled it
- A meta-analysis of blood cytokine network alterations in psychiatric patients: comparisons between schizophrenia, bipolar disorder and depression.Molecular psychiatry · 2016Pooled it
- Article
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- Perceived socioeconomic vulnerability, but not objective poverty, is linked to interoception through perceived stress.Frontiers in psychology · 2026Article
- The mediating role of job fairness and job burnout between subjective social status and depressive symptoms in Chinese migrant workers: a generational difference analysis.BMC public health · 2025Article
- Contributions of subjective status to eating behaviors, obesity, and metabolic health across development.Appetite · 2025Review
- The role of the microbiota-gut-brain axis in schizophrenia: an immunological perspective.Frontiers in immunology · 2025Review
- Writing tips for psychoneuroimmunology trainees: Lessons learned from Dr. Kiecolt-Glaser.Comprehensive psychoneuroendocrinology · 2024Article
- The Influence of Social Dynamics on Biological Aging and the Health of Historically Marginalized Populations: A Biopsychosocial Model for Health Disparities.International journal of environmental research and public health · 2024Review
- Subjective Social Status and Longitudinal Changes in Systemic Inflammation.Annals of behavioral medicine : a publication of the Society of Behavioral Medicine · 2023Article
- Age and Sex Differences in the Associations Among Socioeconomic Status, Affective Reactivity to Daily Stressors, and Physical Health in the MIDUS Study.Annals of behavioral medicine : a publication of the Society of Behavioral Medicine · 2023Article
- Subjective social status, race, and metabolic syndrome in women with breast cancer.Breast cancer research and treatment · 2023Article
- First-generation College Students Have Greater Systemic Inflammation than Continuing-Generation College Students Following the Initial College Transition: A Brief Report.Annals of behavioral medicine : a publication of the Society of Behavioral Medicine · 2023Article
- Predict, prevent and manage moral injuries in Canadian frontline healthcare workers and leaders facing the COVID-19 pandemic: Protocol of a mixed methods study.SSM. Mental health · 2022Article
- A protective rung on the ladder? How past and current social status shaped changes in health during COVID-19.SSM - population health · 2022Article
- Frequent Interpersonal Stress and Inflammatory Reactivity Predict Depressive-Symptom Increases: Two Tests of the Social-Signal-Transduction Theory of Depression.Psychological science · 2022Article
- Childhood maltreatment, subjective social status, and health disparities in bereavement.Psychoneuroendocrinology · 2022Article
Corrections and comments
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Authors and funding
6 authors at 3 institutions in 1 country.
Funding
Abstract
Growing evidence suggests that lower subjective social status (SSS), which reflects where a person positions himself on a social ladder in relation to others, is independently related to poor health. People who rate themselves lower in status also experience more frequent stressors and report higher stress than those who rate themselves higher in status, and chronic stress can enhance an individual's response to subsequent stressors. To address whether SSS predicted stress-induced interleukin-6 (IL-6) changes, we assessed 138 healthy adults at rest and following the Trier Social Stress Test (TSST). Participants completed the TSST at two study visits, separated by 4 months. People who placed themselves lower on the social ladder had larger IL-6 responses from baseline to 45 min post-stressor (p=0.01) and from baseline to 2h post-stressor (p=0.03) than those who placed themselves higher on the social ladder. Based on a ratio of subjective threat and coping ratings of the stress task, participants who viewed themselves as lower in status also tended to rate the speech task as more threatening and less manageable than those who viewed themselves as higher in status (p=0.05). These data suggest that people with lower perceived status experience greater physiological and psychological burden from brief stressors compared to those with higher perceived status. Accordingly, responses to stressors may be a possible mechanistic link among SSS, stress, and health.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.