Evidence map›Paper›PMID 23847728›Full record

ArticleBiomedical optics express2013

Automated tissue characterization of in vivo atherosclerotic plaques by intravascular optical coherence tomography images.

Giovanni Jacopo Ughi, Tom Adriaenssens, Peter Sinnaeve, Walter Desmet, Jan D'hooge

Abstract read
In one paragraph

Article in Biomedical optics express, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 51 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
51citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

51 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Histology-Grounded Automated Plaque Subtype Segmentation in Intravascular Optical Coherence Tomography.Journal of the Society for Cardiovascular Angiography & Interventions · 2025
    Article
  8. Article
  9. Article
  10. Sk-Conv and SPP-based UNet for lesion segmentation of coronary optical coherence tomography.Technology and health care : official journal of the European Society for Engineering and Medicine · 2023
    Article
  11. Article
  12. Recent Trends in Artificial Intelligence-Assisted Coronary Atherosclerotic Plaque Characterization.International journal of environmental research and public health · 2021
    Review
  13. Article
  14. Article
  15. Review
  16. Article
  17. Article
  18. Article
  19. Biomedical optics express · 2020
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Giovanni Jacopo UghiCardiovascular Diseases, University Hospitals Leuven, and Dept. of Cardiovascular Sciences, KU Leuven, Belgium.
Tom Adriaenssens
Peter Sinnaeve
Walter Desmet
Jan D'hooge

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Intravascular optical coherence tomography (IVOCT) is rapidly becoming the method of choice for the in vivo investigation of coronary artery disease. While IVOCT visualizes atherosclerotic plaques with a resolution <20µm, image analysis in terms of tissue composition is currently performed by a time-consuming manual procedure based on the qualitative interpretation of image features. We illustrate an algorithm for the automated and systematic characterization of IVOCT atherosclerotic tissue. The proposed method consists in a supervised classification of image pixels according to textural features combined with the estimated value of the optical attenuation coefficient. IVOCT images of 64 plaques, from 49 in vivo IVOCT data sets, constituted the algorithm's training and testing data sets. Validation was obtained by comparing automated analysis results to the manual assessment of atherosclerotic plaques. An overall pixel-wise accuracy of 81.5% with a classification feasibility of 76.5% and per-class accuracy of 89.5%, 72.1% and 79.5% for fibrotic, calcified and lipid-rich tissue respectively, was found. Moreover, measured optical properties were in agreement with previous results reported in literature. As such, an algorithm for automated tissue characterization was developed and validated using in vivo human data, suggesting that it can be applied to clinical IVOCT data. This might be an important step towards the integration of IVOCT in cardiovascular research and routine clinical practice.

Indexed as

(100.0100) Image processing(100.2960) Image analysis(100.4995) Pattern recognition, metrics(170.0170) Medical optics and biotechnology(170.6935) Tissue characterization

Identifiers

PMID23847728
PMCPMC3704084

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.