Evidence map›Paper›PMID 23847725›Full record

ArticleBiomedical optics express2013

Influence of probe pressure on the diffuse correlation spectroscopy blood flow signal: extra-cerebral contributions.

Rickson C Mesquita, Steven S Schenkel, David L Minkoff, Xiangping Lu, Christopher G Favilla, Patrick M Vora, David R Busch, Malavika Chandra, Joel H Greenberg, John A Detre and 1 more

Abstract read
In one paragraph

Article in Biomedical optics express, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers.

0numbers the graph read from it
0cells of the map it votes in
47citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

47 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Rickson C MesquitaDepartment of Physics & Astronomy, University of Pennsylvania, 3231 Walnut St., Philadelphia, PA 19104, USA ; Institute of Physics, University of Campinas, 777 Sergio Buarque de Holanda St., Campinas, SP 13083-859, Brazil.
Steven S Schenkel
David L Minkoff
Xiangping Lu
Christopher G Favilla
Patrick M Vora
David R Busch
Malavika Chandra
Joel H Greenberg
John A Detre
A G Yodh

Funding

Training and DisseminationP41EB015893 · NIBIB · UNIVERSITY OF PENNSYLVANIA · PI REDDY, RAVINDER · 2012 to 2019
$11.3M
Diffuse Optics for Acute Stroke ManagementR01NS060653 · NINDS · UNIVERSITY OF PENNSYLVANIA · PI YODH, ARJUN G. · 2008 to 2018
$5.5M
Augmented Physiologic Monitoring to Predict Brain Injury in Infants with CHDR01NS072338 · NINDS · CHILDREN'S HOSP OF PHILADELPHIA · PI LICHT, DANIEL JACQUES · 2011 to 2015
$1.7M
Mentoring and research in translational neuroimagingK24NS058386 · NINDS · UNIVERSITY OF PENNSYLVANIA · PI DETRE, JOHN A · 2007 to 2011
$597k
NIBIB NIH HHS P41 EB015893NINDS NIH HHS K24 NS058386NINDS NIH HHS R01 NS060653NINDS NIH HHS R01 NS072338
6 · The paper itself

Abstract

A pilot study explores relative contributions of extra-cerebral (scalp/skull) versus brain (cerebral) tissues to the blood flow index determined by diffuse correlation spectroscopy (DCS). Microvascular DCS flow measurements were made on the head during baseline and breath-holding/hyperventilation tasks, both with and without pressure. Baseline (resting) data enabled estimation of extra-cerebral flow signals and their pressure dependencies. A simple two-component model was used to derive baseline and activated cerebral blood flow (CBF) signals, and the DCS flow indices were also cross-correlated with concurrent Transcranial Doppler Ultrasound (TCD) blood velocity measurements. The study suggests new pressure-dependent experimental paradigms for elucidation of blood flow contributions from extra-cerebral and cerebral tissues.

Indexed as

(170.2655) Functional monitoring and imaging(170.3660) Light propagation in tissues(170.3880) Medical and biological imaging(170.6480) Spectroscopy, speckle

Identifiers

PMID23847725
PMCPMC3704102

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.