ArticleFrontiers in immunology2013
Decoys and Regulatory "Receptors" of the IL-1/Toll-Like Receptor Superfamily.
Article in Frontiers in immunology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.
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Who cites it
33 citing papers in PubMed.
- Molecular cytokine-dependent mechanisms of periodontitis pathogenesis and the potential for pharmacological IL-1 modulation in disease treatment.Frontiers in dental medicine · 2026Review
- Integrated airway epithelial signaling networks linking allergen-driven inflammation to airway remodeling in asthma.Frontiers in immunology · 2026Review
- Treating and triggering hyperinflammation: tackling hemophagocytic lymphohistiocytosis and HLH-like syndromes in the pediatric cell therapy and critical care setting.Frontiers in oncology · 2025Review
- A cytokine/PTX3 prognostic index as a predictor of mortality in sepsis.Frontiers in immunology · 2022Article
- Induction of Unique STAT Heterodimers by IL-21 Provokes IL-1RI Expression on CD8Immune network · 2021Article
- Interleukin-1α dependent survival of cardiac fibroblasts is associated with StAR/STARD1 expression and improved cardiac remodeling and function after myocardial infarction.Journal of molecular and cellular cardiology · 2021Article
- Interleukin-37 regulates innate immune signaling in human and mouse colonic organoids.Scientific reports · 2021Article
- Induction of the IL-1RII decoy receptor by NFAT/FOXP3 blocks IL-1β-dependent response of Th17 cells.eLife · 2021Article
- Human recombinant interleukin-38 suppresses inflammation in mouse models of local and systemic disease.Cytokine · 2021Article
- Biomarkers for Temporomandibular Disorders: Current Status and Future Directions.Diagnostics (Basel, Switzerland) · 2020Review
- The Society for Immunotherapy of Cancer perspective on regulation of interleukin-6 signaling in COVID-19-related systemic inflammatory response.Journal for immunotherapy of cancer · 2020Article
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- Young and aged TLR4 deficient mice show sex-dependent enhancements in spatial memory and alterations in interleukin-1 related genes.Brain, behavior, and immunity · 2019Article
- Overview of the IL-1 family in innate inflammation and acquired immunity.Immunological reviews · 2018Review
- Perspective on the Development and Validation of Ab Reagents to Fish Immune Proteins for the Correct Assessment of Immune Function.Frontiers in immunology · 2018Article
- MiR-30a targets IL-1α and regulates islet functions as an inflammation buffer and response factor.Scientific reports · 2017Article
- Interleukin 37 expression in mice alters sleep responses to inflammatory agents and influenza virus infection.Neurobiology of sleep and circadian rhythms · 2017Article
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Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Members of the IL-1 family play a key role in innate and adaptive immunity and in the pathogenesis of diverse diseases. Members of IL-1R like receptor (ILR) family include signaling molecules and negative regulators. The latter include decoy receptors (IL-1RII; IL-18BP) and "receptors" with regulatory function (TIR8/SIGIRR; IL-1RAcPb; DIGIRR). Structural considerations suggest that also TIGIRR-1 and IL-1RAPL may have regulatory function. The presence of multiple pathways of negative regulation of members of the IL-1/IL-1R family emphasizes the need for a tight control of members of this fundamental system.
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