ArticleFrontiers in microbiology2013
Of energy and survival incognito: a relationship between viable but non-culturable cells formation and inorganic polyphosphate and formate metabolism in Campylobacter jejuni.
Article in Frontiers in microbiology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
11 citing papers in PubMed, 31 citations in OpenAlex.
- Overview of VBNC, a survival strategy for microorganisms.3 Biotech · 2022Review
- Longitudinal Changes inApplied and environmental microbiology · 2022Article
- Association of Broiler Litter Microbiome Composition andFrontiers in veterinary science · 2021Article
- Formic Acid as an Antimicrobial for Poultry Production: A Review.Frontiers in veterinary science · 2020Review
- Essential Oils as an Intervention Strategy to ReduceFrontiers in microbiology · 2019Review
- Detection and Quantification of Viable but Non-culturableFrontiers in microbiology · 2019Article
- Polyphosphate and associated enzymes as global regulators of stress response and virulence in Campylobacter jejuni.World journal of gastroenterology · 2016Review
- Transcriptome analysis of Campylobacter jejuni polyphosphate kinase (ppk1 and ppk2) mutants.Virulence · 2015Article
- Regulation of oxidative stress resistance in Campylobacter jejuni, a microaerophilic foodborne pathogen.Frontiers in microbiology · 2015Review
- Non-selective regulation of peroxide and superoxide resistance genes by PerR in Campylobacter jejuni.Frontiers in microbiology · 2015Article
- Microbial mechanisms of tolerance to weak acid stress.Frontiers in microbiology · 2013Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Campylobacter jejuni is a Gram-negative food-borne bacterium that can cause mild to serious diseases in humans. A variety of stress conditions including exposure to formic acid, a weak organic acid, can cause C. jejuni to form viable but non-culturable cells (VBNC), which was proposed as a potential survival mechanism. The inability to detect C. jejuni VBNC using standard culturing techniques may increase the risk of exposure to foods contaminated with this pathogen. However, little is known about the cellular mechanisms and triggers governing VBNC formation. Here, we discuss novel mechanisms that potentially affect VBNC formation in C. jejuni and emphasize the impact of formic acid on this process. Specifically, we highlight findings that show that impairing inorganic polyphosphate (poly-P) metabolism reduces the ability of C. jejuni to form VBNC in a medium containing formic acid. We also discuss the potential effect of poly-P and formate metabolism on energy homeostasis and cognate VBNC formation. The relationship between poly-P metabolism and VBNC formation under acid stress has only recently been identified and may represent a breakthrough in understanding this phenomenon and its impact on food safety.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.