Evidence map›Paper›PMID 23847516›Full record

ArticleFrontiers in human neuroscience2013

Facilitated acquisition of eyeblink conditioning in those vulnerable to anxiety disorders.

Meghan D Caulfield, J Devin McAuley, Richard J Servatius

Abstract read
In one paragraph

Article in Frontiers in human neuroscience, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Meghan D CaulfieldGraduate School of Biomedical Sciences, University of Medicine and Dentistry of New Jersey Newark, NJ, USA ; New Jersey Medical School, Stress and Motivated Behavior Institute, University of Medicine and Dentistry of New Jersey Newark, NJ, USA.
J Devin McAuley
Richard J Servatius

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Behavioral inhibition (BI) increases vulnerability to develop anxiety disorders and is typified by avoidance and withdrawal from novel objects, people, and situations. The present study considered the relationship between BI and temperamental risk factors, such as trait anxiety and acquisition rate of a classically conditioned eyeblink response. One-hundred seventy-four healthy undergraduate students (mean age 20.3 years, 71.8% female) were given the State-Trait Anxiety Inventory and a battery of self-report measures of BI consisting of the Adult and Retrospective Measures of Behavioral Inhibition (AMBI/RMBI) and the Concurrent and Retrospective Self Report of Inhibition (CSRI/RSRI). Participants then underwent standard delay classical eyeblink conditioning consisting of 45 trials with a 500-ms CS overlapping and co-terminating with a 10-ms airpuff US. Individuals with higher scores on the AMBI and Trait Anxiety Inventory, but not the other measures, showed faster acquisition of a conditioned eyeblink response than individuals with lower scores. Results support a relationship between facilitated acquisition of inter-stimulus relationships and risk for anxiety, and suggest that some measures assessing anxiety vulnerability better capture this relationship than others.

Indexed as

anxietyanxiety vulnerabilitybehavioral inhibitionclassical eyeblink conditioningtemperamenttrait anxiety

Identifiers

PMID23847516
PMCPMC3701872

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.