Evidence map›Paper›PMID 23847220›Full record

GuidelineJournal of the National Comprehensive Cancer Network : JNCCN2013

Myelodysplastic syndromes: clinical practice guidelines in oncology.

Peter L Greenberg, Eyal Attar, John M Bennett, Clara D Bloomfield, Uma Borate, Carlos M De Castro, H Joachim Deeg, Olga Frankfurt, Karin Gaensler, Guillermo Garcia-Manero and 14 more

Registry-linked trialAbstract readPractice Guideline
In one paragraph

Guideline in Journal of the National Comprehensive Cancer Network : JNCCN, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02193880 (Safety of Post-transplant Alpha-beta Depleted T-cell Infusion Following Haploidentical Stem Cell Transplant), which is not on this map. Cited by 42 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
42citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02193880 nacompletednot on this mapstarted 2014, after this paper: background citation

Safety of Post-transplant Alpha-beta Depleted T-cell Infusion Following Haploidentical Stem Cell Transplant (Haplo SCT)

TypeinterventionalSponsorAyman SaadRan2014 to 2018Enrolled7ConditionsHematologic Neoplasms, Graft-Versus-Host DiseaseArmsAlpha-beta depleted T-cell infusion after post-transplant cyclophosphamide.
3 · Its place in the literature

Who cites it

42 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Guideline
  4. Trial
  5. Trial
  6. GATA2 deficiency exacerbates chronic liver injuryWorld journal of stem cells · 2026
    Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. The Clinical Efficacy of Epoetin Alfa and Darbepoetin Alfa in Patients with Low-Risk or Intermediate-1-Risk Myelodysplastic Syndrome: Retrospective Multi-center Real-Life Study.Indian journal of hematology & blood transfusion : an official journal of Indian Society of Hematology and Blood Transfusion · 2022
    Article
  12. Article
  13. Article
  14. Review
  15. Updates on Novel Erythropoiesis-Stimulating Agents: Clinical and Molecular Approach.Indian journal of hematology & blood transfusion : an official journal of Indian Society of Hematology and Blood Transfusion · 2020
    Review
  16. Article
  17. The MDS genomics-prognosis symbiosis.Hematology. American Society of Hematology. Education Program · 2018
    Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

24 authors.

Peter L GreenbergStanford Cancer Institute, USA.
Eyal Attar
John M Bennett
Clara D Bloomfield
Uma Borate
Carlos M De Castro
H Joachim Deeg
Olga Frankfurt
Karin Gaensler
Guillermo Garcia-Manero
Steven D Gore
David Head
Rami Komrokji
Lori J Maness
Michael Millenson
Margaret R O'Donnell
Paul J Shami
Brady L Stein
Richard M Stone
James E Thompson
Peter Westervelt
Benton Wheeler
Dorothy A Shead
Maoko Naganuma

Funding

Tumor Evolution and Metastasis ProgramP30CA016672 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI Scott Kopetz · 1985 to 2026
$290.8M
Targeting Epigenomics in Myeloid NeoplasmsK24CA111717 · NCI · YALE UNIVERSITY · PI GORE, STEVEN D · 2005 to 2015
$1.7M
NCI NIH HHS K24 CA111717NCI NIH HHS P30 CA016672
6 · The paper itself

Abstract

The myelodysplastic syndromes (MDS) represent a heterogeneous group of clonal hematopoietic disorders characterized by cytopenias, dysplasia in one or more myeloid lineages, and the potential for development of acute myeloid leukemia. These disorders primarily affect older adults. The NCCN Clinical Practice Guidelines in Oncology for MDS provide recommendations on the diagnostic evaluation and classification of MDS, risk evaluation according to established prognostic assessment tools (including the new revised International Prognostic Scoring System), treatment options according to risk categories, and management of related anemia.

Indexed as

AnemiaAntineoplastic AgentsHematinicsHematopoietic Stem Cell TransplantationHumansImmunologic FactorsMyelodysplastic SyndromesPrognosisTransplantation, HomologousAntineoplastic AgentsHematinicsImmunologic Factors

Identifiers

PMID23847220
PMCPMC4000017

What OpenQuestion holds

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Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.