ArticleProceedings of the National Academy of Sciences of the United States of America2013
Systems approaches map regulatory networks downstream of the auxin receptor AFB3 in the nitrate response of Arabidopsis thaliana roots.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 94 papers.
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94 citing papers in PubMed, 218 citations in OpenAlex.
- The NRT1.1-NLP7 Nexus: An Integrative Signaling Nexus from Nitrate Sensing to Systemic Adaptation and Structure-Guided Engineering.Plants (Basel, Switzerland) · 2026Review
- A feedback regulatory loop by MAPK-CCA1 engages auxin signalling to stimulate root foraging for nitrate.Nature plants · 2026Article
- Decoding nitrogen uptake efficiency in maize and sorghum: insights from comparative gene regulatory networks.The Plant journal : for cell and molecular biology · 2025Article
- Evolutionary trajectory of the NPF6.3(NRT1.1/CHL1)-centered nitrate signaling regulatory network in plant roots.BMC plant biology · 2025Article
- Involvement of the miR156/SPLs/NLP7 modules in plant lateral root development and nitrogen uptake.Planta · 2025Article
- HaNAC146 from sunflower overexpression enhances plant growth and stress tolerance.Plant cell reports · 2025Article
- Genome-Wide Identification ofInternational journal of molecular sciences · 2024Article
- NIN-LIKE PROTEIN3.2 inhibits repressor Aux/IAA14 expression and enhances root biomass in maize seedlings under low nitrogen.The Plant cell · 2024Article
- Genome-Wide Identification, Expression, and Interaction Analysis of the Auxin Response Factor andInternational journal of molecular sciences · 2024Article
- Article
- Auxin synthesis promotes N metabolism and optimizes root structure enhancing N acquirement in maize (Zea mays L.).Planta · 2024Article
- Functional analyses of the NRT2 family of nitrate transporters inFrontiers in plant science · 2024Review
- Protein Phosphorylation Orchestrates Acclimations of Arabidopsis Plants to Environmental pH.Molecular & cellular proteomics : MCP · 2024Article
- Genetic regulation of lateral root development.Plant signaling & behavior · 2023Review
- miRNA mediated regulation of nitrogen response and nitrogen use efficiency of plants: the case of wheat.Physiology and molecular biology of plants : an international journal of functional plant biology · 2023Article
- Whole genome sequencing and analysis of multiple isolates of Ceratocystis destructans, the causal agent of Ceratocystis canker of almond in California.Scientific reports · 2023Article
- Plant nitrogen availability and crosstalk with phytohormones signallings and their biotechnology breeding application in crops.Plant biotechnology journal · 2023Review
- The nitrate transporter NRT2.1 directly antagonizes PIN7-mediated auxin transport for root growth adaptation.Proceedings of the National Academy of Sciences of the United States of America · 2023Article
- The PtoTCP20-miR396d-PtoGRF15 module regulates secondary vascular development in Populus.Plant communications · 2023Article
- Alkalinity modulates a unique suite of genes to recalibrate growth and pH homeostasis.Frontiers in plant science · 2023Article
34 more citing papers are in PubMed but not listed here.
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Auxin is a key phytohormone regulating central processes in plants. Although the mechanism by which auxin triggers changes in gene expression is well understood, little is known about the specific role of the individual members of the TIR1/AFB auxin receptors, Aux/IAA repressors, and ARF transcription factors and/or molecular pathways acting downstream leading to plant responses to the environment. We previously reported a role for AFB3 in coordinating primary and lateral root growth to nitrate availability. In this work, we used an integrated genomics, bioinformatics, and molecular genetics approach to dissect regulatory networks acting downstream of AFB3 that are activated by nitrate in roots. We found that the NAC4 transcription factor is a key regulatory element controlling a nitrate-responsive network, and that nac4 mutants have altered lateral root growth but normal primary root growth in response to nitrate. This finding suggests that AFB3 is able to activate two independent pathways to control root system architecture. Our systems approach has unraveled key components of the AFB3 regulatory network leading to changes in lateral root growth in response to nitrate.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.