Evidence map›Paper›PMID 23846598›Full record

ReviewNeuroscience bulletin2013

Signaling pathways that regulate axon regeneration.

Saijilafu, Bo-Yin Zhang, Feng-Quan Zhou

Abstract readReview
In one paragraph

Review in Neuroscience bulletin, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Review
  6. Article
  7. Review
  8. Article
  9. Article
  10. Time course analysis of sensory axon regenerationNeural regeneration research · 2020
    Article
  11. Review
  12. Article
  13. Article
  14. Review
  15. Article
  16. Article
  17. An update on spinal cord injury research.Neuroscience bulletin · 2013
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

SaijilafuDepartment of Orthopaedic Surgery, The Johns Hopkins University, Baltimore, Maryland, USA.
Bo-Yin Zhang
Feng-Quan Zhou

Funding

Role of CLASP in neuronal morphogenesis during developmentR01NS064288 · NINDS · JOHNS HOPKINS UNIVERSITY · PI ZHOU, FENGQUAN · 2009 to 2013
$1.8M
NINDS NIH HHS R01 NS064288NINDS NIH HHS R01NS064288
6 · The paper itself

Abstract

Neurons in the mammalian central nervous system (CNS) cannot regenerate axons after injury. in contrast, neurons in the mammalian peripheral nervous system and in some non-mammalian models, such as C. elegans and Drosophila, are able to regrow axons. Understanding the molecular mechanisms by which these neurons support axon regeneration will help us find ways to enhance mammalian CNS axon regeneration. Here, recent studies in which signaling pathways regulating naturally-occurring axon regeneration that have been identified are reviewed, focusing on how these pathways control gene expression and growth-cone function during axon regeneration.

Indexed as

AnimalsAxonsBrain InjuriesNerve RegenerationSignal TransductionSpinal Cord Injuries

Identifiers

PMID23846598
PMCPMC5561939

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.