ArticleJournal of pediatric surgery2013
Wilms tumor survival in Kenya.
Article in Journal of pediatric surgery, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 2 of them syntheses that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
24 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Spotting childhood abdominal tumours: a systematic review and meta-analysis of the clinical presentation.Archives of disease in childhood · 2026Pooled it
- Funding paediatric surgery procedures in sub-Saharan Africa.Malawi medical journal : the journal of Medical Association of Malawi · 2019Pooled it
- Hope and challenges in the diagnosis and treatment of Wilms tumor: a single-center retrospective study in China.Frontiers in pediatrics · 2025Article
- The outcomes of children with primary malignant renal tumors: a 14-year single-center experience.BMC cancer · 2024Article
- Current status and future perspectives of wilms tumor treatment in Iran.Annals of medicine and surgery (2012) · 2023Article
- Article
- Wilms tumour treatment in Sudan: A 10-year single-centre experience.Cancer reports (Hoboken, N.J.) · 2022Article
- The magnitude and perceived reasons for childhood cancer treatment abandonment in Ethiopia: from health care providers' perspective.BMC health services research · 2022Article
- Nephroblastoma Treatment and Outcomes in a Low-Income Setting.JCO global oncology · 2022Article
- Wilms Tumor in Sub-Saharan Africa: Molecular and Social Determinants of a Global Pediatric Health Disparity.Frontiers in oncology · 2020Review
- Investigating Wilms' Tumours Worldwide: A Report of the OxPLORE Collaboration-A Cross-Sectional Observational Study.World journal of surgery · 2020Observational
- FXR1 expression domain in Wilms tumor.Journal of pediatric surgery · 2019Article
- Pediatric Solid Tumors in Resource-Constrained Settings: A Review of Available Evidence on Management, Outcomes, and Barriers to Care.Children (Basel, Switzerland) · 2018Review
- Pediatric Cancer in Northern Tanzania: Evaluation of Diagnosis, Treatment, and Outcomes.Journal of global oncology · 2018Article
- Establishing a Pediatric Hematology-Oncology Program in Botswana.Journal of global oncology · 2018Article
- Wilms Tumor Treatment Outcomes: Perspectives From a Low-Income Setting.Journal of global oncology · 2017Article
- Treating Nephroblastoma in Rwanda: Using International Society of Pediatric Oncology Guidelines in a Novel Oncologic Care Model.Journal of global oncology · 2016Article
- Outcome of childhood malignancies at the University of Port Harcourt Teaching Hospital: a call for implementation of palliative care.African health sciences · 2016Article
- Genetic and chromosomal alterations in Kenyan Wilms Tumor.Genes, chromosomes & cancer · 2015Article
- Risk factors for abandonment of Wilms tumor therapy in Kenya.Pediatric blood & cancer · 2015Article
Corrections and comments
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Authors and funding
20 authors.
Funding
Abstract
purposeSurvival from Wilms Tumor (WT) exceeds 90% at 5 years in developed nations, whereas at last report, 2-year event-free survival (EFS) in Kenya reached only 35%. To clarify factors linked to these poor outcomes in Kenya, we established a comprehensive web-based WT registry, comprised of patients from the four primary hospitals treating childhood cancers. MATERIALS AND
methodsWT patients diagnosed between January 2008 and January 2012 were identified. Files were abstracted for demographic characteristics, treatment regimens, and enrollment in the Kenyan National Hospital Insurance Fund (NHIF). Children under 15 years of age having both a primary kidney tumor on imaging and concordant histology consistent with WT were included.
resultsTwo-year event-free survival (EFS) was 52.7% for all patients (n=133), although loss to follow up (LTFU) was 50%. For the 33 patients who completed all scheduled standard therapy, 2-year EFS was 94%. Patients enrolled in NHIF tended to complete more standard therapy and had a lower hazard of death (Cox 0.192, p < 0.001).
conclusionSurvival of Kenyan WT patients has increased slightly since last report. Notably, WT patients completing all phases of standard therapy experienced 2-year survival approaching the benchmarks of developed nations. Efforts in Kenya should be made to enhance compliance with WT treatment through NHIF enrollment.
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