Evidence map›Paper›PMID 23845514›Full record

ReviewPsychoneuroendocrinology2013

Psychosocial factors and hematopoietic stem cell transplantation: potential biobehavioral pathways.

Jennifer M Knight, Jeffrey M Lyness, Olle Jane Z Sahler, Jane L Liesveld, Jan A Moynihan

Open access · greenAbstract readReview
In one paragraph

Review in Psychoneuroendocrinology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 55 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Jennifer M KnightDepartment of Psychiatry and Behavioral Medicine, Medical College of Wisconsin, United States. Electronic address: jmknight@mcw.edu.
Jeffrey M Lyness
Olle Jane Z Sahler
Jane L Liesveld
Jan A Moynihan
University of Rochester Medical Center · USCal Humanities · USMedical College of Wisconsin · US

Funding

The Rochester Center for Mind-Body ResearchR24AG031089 · NIA · UNIVERSITY OF ROCHESTER · PI MOYNIHAN, JAN A · 2007 to 2009
$3.0M
Postdoctoral Training in Geriatric Psychiatry ResearchT32MH073452 · NIMH · UNIVERSITY OF ROCHESTER · PI LYNESS, JEFFREY M · 2005 to 2009
$798k
NIA NIH HHS 5R24 AG031089NIA NIH HHS R24 AG031089NIMH NIH HHS T32 MH073452
6 · The paper itself

Abstract

While psychosocial factors are known to affect cancer progression via biobehavioral pathways in many patient populations, these relationships remain largely unexplored in hematopoietic stem cell transplant (HCT) patients. The purpose of this paper is to critically review the literature regarding psychosocial and endocrine/immune aspects of HCT, with an emphasis on exploring pathways that may mediate the associations between psychosocial factors and disease outcomes. These include the roles of catecholamines, glucocorticoids, inflammation, vascular endothelial growth factor (VEGF), immune reconstitution and infectious susceptibility, as well as the new opportunities available in genomics research. We also discuss the implications for potential immunomodulating psychosocial interventions. Elucidating the biological pathways that account for the associations between psychosocial factors and clinical course could ultimately lead to improved outcomes for this psychologically and immunologically vulnerable population.

Indexed as

GenomicsHematopoietic Stem Cell TransplantationHumansImmunomodulationNeoplasmsTreatment OutcomeCMVC-reactive proteinCRPcytomegalovirusgraft-versus-host-diseaseGVHDHCThematopoietic stem cell transplantationHematopoietic stem cell transplantationherpes simplex virusHPAHSVhypothalamic–pituitary–adrenalnatural killerNKPNEPNIpsychoneuroendocrinologyPsychoneuroendocrinologypsychoneuroimmunologyPsychoneuroimmunologyPsychooncologyPsychosocial factorsSIRSsystemic inflammatory response syndromevascular endothelial growth factorVEGF

Identifiers

PMID23845514
PMCPMC3812389
OpenAlexW2098443706

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.